Baloxavir Impurity 12 CAS 2136287-88-0
| CAS No. | 2136287-88-0 |
| Molecular Formula | C30H31F2N3O4S |
| Molecular Weight | 567.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Baloxavir Impurity 12 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Baloxavir Impurity 12 (CAS 2136287-88-0) is a certified pharmaceutical impurity reference standard with the molecular formula C30H31F2N3O4S and a molecular weight of 567.65 g/mol.
Baloxavir Impurity 12 (C30H31F2N3O4S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C30H31F2N3O4S |
| Molecular Weight | 567.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Baloxavir Standards
- Baloxavir Impurity 115 (CAS CATO-C4X-2108115)
- Baloxavir Impurity 13 (CAS 2136287-69-7)
- Baloxavir Impurity 14 (CAS CATO-C4X-210814)
- Baloxavir Impurity 15 (CAS CATO-C4X-210815)
- Baloxavir Marboxil Impurity 207 (CAS CATO-C4X-2108207)
- Baloxavir Marboxil Impurity 208 (CAS CATO-C4X-2108208)
- Baloxavir Marboxil Impurity 224 (CAS CATO-C4X-2108224)
- Baloxavir Impurity 53 (CAS CATO-C4X-210853)
Recommended Standards
- (3aR,8aR)-N,N-Diethyltetrahydro-2,2-dimethyl-4,4,8,8-tetraphenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-amine (CAS 946514-47-2)
- Cefcapene Impurity 78 (CAS CATO-C4X-182478)
- Δ2-Cefcapene Pivoxil (CAS CATO-C4X-18244)
- Cefcapene Impurity 28 (CAS CATO-C4X-182428)
- Candesartan Impurity 7 (CAS CATO-C4X-15727)
- Fudosteine Impurity 10 (CAS CATO-C4X-144710)
- Loxoprofen Impurity 30 (CAS 308279-38-1)
- (S)-2-(4-methylmorpholin-3-yl)ethan-1-ol (CAS 2165811-54-9)
- (R)-1-(2,4-dimethylbenzyl)pyrrolidin-3-amine (CAS 730241-93-7)
- (Morpholinomethylene)bis(phosphonic acid) (CAS 32545-75-8)
- tert-butyl trans-3-chlorosulfonylcyclobutanecarboxylate (CAS 1989638-22-3)
- {2-[(4-methylpiperazin-1-yl)methyl]phenyl}methanamine (CAS 879896-50-1)
- 3-Ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine (CAS 1350351-04-0)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com