Bisoprolol Impurity 54 CAS 2137091-22-4
| CAS No. | 2137091-22-4 |
| Molecular Formula | C9H19Cl2NO2 |
| Molecular Weight | 244.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Bisoprolol Impurity 54 (CAS 2137091-22-4), a pharmacopoeial impurity reference standard (molecular formula C9H19Cl2NO2, MW 244.16 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Bisoprolol Impurity 54 (C9H19Cl2NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H19Cl2NO2 |
| Molecular Weight | 244.16 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Bisoprolol Standards
- Bisoprolol EP Impurity A (CAS 62572-93-4)
- Bisoprolol Impurity 94 (CAS CATO-C4X-124794)
- Bisoprolol Impurity 97 (CAS CATO-C4X-124797)
- Bisoprolol Impurity 105 (CAS CATO-C4X-1247105)
- Bisoprolol Impurity 106 (CAS CATO-C4X-1247106)
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- Bisoprolol Impurity 70 (CAS 84425-10-5)
- Bisoprolol Impurity 100 (CAS CATO-C4X-1247100)
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- 2-Isobutyl-5-methoxypyridazin-3(2H)-one (CAS 2059999-12-9)
- 2-Chloro-4-(piperidin-3-yloxy)benzonitrile (CAS 902836-92-4)
- N-(5-Chloro-2-methoxyphenyl)-2-((1-(4-methoxyphenyl)-1H-imidazol-2-yl)thio)acetamide (CAS 688336-08-5)
- PtdIns-(3,4,5)-P3-biotinamide (sodium salt) (CAS 1415684-80-8)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com