6-Chloro-3-hydroxy-2,4-dimethylbenzenesulfonyl chloride CAS 2138044-63-8
| CAS No. | 2138044-63-8 |
| Molecular Formula | C8H8Cl2O3S |
| Molecular Weight | 255.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Chloro-3-hydroxy-2,4-dimethylbenzenesulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-Chloro-3-hydroxy-2,4-dimethylbenzenesulfonyl chloride (CAS 2138044-63-8), a certified reference material (molecular formula C8H8Cl2O3S, MW 255.12 g/mol) for analytical method development and quality control.
Structurally, 6-Chloro-3-hydroxy-2,4-dimethylbenzenesulfonyl chloride (C8H8Cl2O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 255.12 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-3-hydroxy-2,4-dimethylbenzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8Cl2O3S |
| Molecular Weight | 255.12 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-4-ethoxybenzenesulfonyl chloride (CAS 1016729-08-0)
- (5-Chloro-2-methoxyphenyl)methanesulfonyl chloride (CAS 1179047-05-2)
- (3-Chloro-4-methoxyphenyl)methanesulfonyl chloride (CAS 1194375-53-5)
- 2-Chloro-6-(5-chlorothiophen-2-yl)pyridine-3-carbonitrile (CAS 1198278-14-6)
- 5-chloro-4-methoxy-2-methylbenzene-1-sulfonyl chloride (CAS 1368747-92-5)
- 3-Chloro-2-(methoxymethyl)benzenesulfonyl chloride (CAS 1538886-60-0)
- 3-chloro-5-(methoxymethyl)benzene-1-sulfonyl chloride (CAS 1549060-12-9)
- 3-Chloro-4-methoxy-2-methylbenzenesulfonyl chloride (CAS 2385031-64-9)
Recommended Standards
- 5-Chloro-2-ethoxybenzenesulfonyl chloride (CAS 928709-67-5)
- Isoquinonline-8-boronic acid pinacol ester (CAS 2379560-77-5)
- 5-Amino-4,6-dichloro-toluene-2-sulfonic acid amide (CAS 857003-78-2)
- N-(4-Amino-2,6-dichlorophenyl)methanesulfonamide (CAS 926265-82-9)
- ESCitalopram N-Oxide (CAS 917482-45-2)
- (2-Methyl-pyrrolidin-2-yl)-morpholin-4-yl-methanone hydrochloride (CAS 1361114-47-7)
- Methyl 3,3-dimethyl-2-oxocycloheptane-1-carboxylate (CAS 1190305-65-7)
- Isopropyl 2-amino-4-phenylthiophene-3-carboxylate (CAS 351157-38-5)
- 2,6-Dimethyl-1H-indole-3-(tert-butylperoxycarboxylate) (CAS 1448259-52-6)
- (αR)-1-(5-Ddifluoromethyl)pyridin-2-yl)ethanamine hydrochloride (CAS 2774613-05-5)
- 6-Methoxy-3-methyl-3,4-dihydronaphthalen-1(2H)-one (CAS 5563-21-3)
- tert-Butyl N-(3-ethynyloxetan-3-yl)carbamate (CAS 1678527-98-4)
- cyclohexylcarbamodithioic acid (CAS 22292-07-5)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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