2-(6-Chloropyridin-3-yl)-2,2-difluoroacetamide CAS 2138149-59-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2138149-59-2
Molecular FormulaC7H5ClF2N2O
Molecular Weight206.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(6-Chloropyridin-3-yl)-2,2-difluoroacetamide CAS 2138149-59-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-(6-Chloropyridin-3-yl)-2,2-difluoroacetamide (CAS 2138149-59-2) is a high-purity analytical reference standard with the molecular formula C7H5ClF2N2O and a molecular weight of 206.58 g/mol.

Structurally, 2-(6-Chloropyridin-3-yl)-2,2-difluoroacetamide (C7H5ClF2N2O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 206.58 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), 2-(6-Chloropyridin-3-yl)-2,2-difluoroacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H5ClF2N2O
Molecular Weight206.58 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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