6-Chloro-2-(2-fluorophenyl)-4H-chromen-4-one CAS 213894-66-7
| CAS No. | 213894-66-7 |
| Molecular Formula | C15H8ClFO2 |
| Molecular Weight | 274.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-(2-fluorophenyl)-4H-chromen-4-one (C15H8ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 6-Chloro-2-(2-fluorophenyl)-4H-chromen-4-one (CAS 213894-66-7), a certified reference material (molecular formula C15H8ClFO2, MW 274.67 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H8ClFO2 |
| Molecular Weight | 274.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-4-fluorophenethyl ethyl oxalate (CAS 1443309-36-1)
- 3-Chloro-5-fluorophenethyl ethyl oxalate (CAS 1443309-55-4)
- 4-Chloro-3-fluorophenethyl ethyl oxalate (CAS 1443343-31-4)
- 6-Chloro-2-(3-fluorophenyl)-4H-chromen-4-one (CAS 213894-72-5)
- 6-Chloro-2-(4-fluorophenyl)-4H-chromen-4-one (CAS 213894-75-8)
- 7-Chloro-2-(4-fluorophenyl)-4H-chromen-4-one (CAS 766511-64-2)
- 5-Chloro-6-(3-cyanophenoxy)nicotinic acid (CAS 1016739-05-1)
- 5-Chloro-6-nitro-2-phenylbenzo[d]oxazole (CAS 102405-44-7)
Recommended Standards
- 2-(4-Chlorophenyl)-6-fluoro-4H-chromen-4-one (CAS 288400-97-5)
- 2-(4-(Chloromethyl)phenyl)-1-methyl-4-(trifluoromethyl)-1H-imidazole (CAS 2446481-81-6)
- 2-(2-Chlorophenyl)-6-fluoro-4H-chromen-4-one (CAS 527751-46-8)
- 1-(2-(2,4-Dichlorophenoxy)propionyl)-4-benzylthiosemicarbazide (CAS 288154-62-1)
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