methyl 3-bromo-6-hydroxy-5-nitropyridine-2-carboxylate CAS 2140305-71-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including methyl 3-bromo-6-hydroxy-5-nitropyridine-2-carboxylate.

CATO supplies methyl 3-bromo-6-hydroxy-5-nitropyridine-2-carboxylate (CAS 2140305-71-9), a certified reference material (molecular formula C7H5BrN2O5, MW 277.03 g/mol) for analytical method development and quality control.

methyl 3-bromo-6-hydroxy-5-nitropyridine-2-carboxylate (C7H5BrN2O5) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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