6-Fluoro-3,4-dihydroisoquinolin-1(2H)-one CAS 214045-84-8
| CAS No. | 214045-84-8 |
| Molecular Formula | C9H8FNO |
| Molecular Weight | 165.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Fluoro-3,4-dihydroisoquinolin-1(2H)-one (C9H8FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-Fluoro-3,4-dihydroisoquinolin-1(2H)-one (CAS 214045-84-8), molecular formula C9H8FNO and molecular weight 165.16 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Fluoro-3,4-dihydroisoquinolin-1(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8FNO |
| Molecular Weight | 165.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
- 6-Fluoro-2,3-dihydroquinolin-4(1H)-one (CAS 38470-26-7)
- 6-Fluoro-3,4-dihydroquinolin-2(1H)-one (CAS 75893-82-2)
- 6-Fluoro-1-methylindolin-2-one (CAS 913240-15-0)
- 6-Fluoro-4-methoxy-1H-indole (CAS 885521-02-8)
- 2,6-Dimethylheptanoic acid (CAS 7494-12-4)
- 2-Chloro-5-iodopyrimidin-4(3H)-one (CAS 1226881-10-2)
- 2-(4-hydroxyphenoxy)propanamide (CAS 127437-43-8)
- 2-Ethyl-1h-benzo[d]imidazole-6-carboxylic acid (CAS 891454-18-5)
- Dicamba-5-hydroxy (CAS 7600-50-2)
- 2-(3-Bromo-2-chloro-5-(trifluoromethyl)phenyl)acetic acid (CAS 2090523-96-7)
- 7-Fluoro-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-4-carbaldehyde (CAS 2768872-27-9)
- 1996-44-7 2,4-DIFLUOROBENZENE-1-THIOL 2,4-DIFLUOROBENZENETHIOL 2,4-DIFLUOROTHIOPHENOL 2,4-Difluorothiophenol(--2,4-Difluorobenzenethiol AS05520 BENZENETHIOL, 2,4-DIFLUORO- (CAS 1996-44-7)
- 4-Allyl-1-fluoro-2-(trifluoromethyl)benzene (CAS 1417461-59-6)
- Cyclopeptide-5 (CAS 197172-76-2)
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