| CAS No. | 21444-62-2 |
| Molecular Formula | C12H8BrN3O3 |
| Molecular Weight | 322.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(5-Bromofuran-2-yl)-1-methyl-5-nitro-1H-benzo[d]imidazole.
2-(5-Bromofuran-2-yl)-1-methyl-5-nitro-1H-benzo[d]imidazole (CAS 21444-62-2), molecular formula C12H8BrN3O3 and molecular weight 322.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(5-Bromofuran-2-yl)-1-methyl-5-nitro-1H-benzo[d]imidazole (C12H8BrN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(5-Bromofuran-2-yl)-1-methyl-5-nitro-1H-benzo[d]imidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C12H8BrN3O3 |
| Molecular Weight | 322.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |