5-Fluoro-6-methylpyrimidin-4-ol hydrochloride CAS 2145-55-3
| CAS No. | 2145-55-3 |
| Molecular Formula | C5H5FN2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 164.56 g/mol gives 5-Fluoro-6-methylpyrimidin-4-ol hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Fluoro-6-methylpyrimidin-4-ol hydrochloride (CAS 2145-55-3) is a high-purity analytical reference standard with the molecular formula C5H5FN2OHCl and a molecular weight of 164.56 g/mol.
The molecular framework of 5-Fluoro-6-methylpyrimidin-4-ol hydrochloride (C5H5FN2OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-6-methylpyrimidin-4-ol hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5FN2O HCl |
| Molecular Weight | 164.56 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-[(2-Fluoro-4-nitrophenoxy)methyl]-1-methylpiperidine (CAS 1000052-54-9)
- 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)aniline (CAS 1000053-56-4)
- 2-Fluoro-5-iodo-4-methoxybenzoic acid (CAS 1000162-78-6)
- Ethyl 4-fluoro-3-ethoxybenzoate (CAS 1000207-63-5)
- 6-fluoro-4-iodo-1H-benzo[d]imidazole (CAS 1000308-33-7)
- 2-Fluoro-3-hydroxybenzonitrile (CAS 1000339-24-1)
- 1-(5-Fluoro-2-methylphenyl)pyrrolidine (CAS 1000339-32-1)
- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- 2-Chloroacridine (CAS 1207-96-1)
- 1,1-Dimethyl-1,2,3,4-tetrahydroisoquinoline (CAS 41565-85-9)
- tert-Butyl (1-(6-chloropyrimidin-4-yl)piperidin-3-yl)carbamate (CAS 939986-09-1)
- 6-Amino-1-methyl-4-thioxo-3,4-dihydro-1,3,5-triazin-2(1H)-one (CAS 77420-23-6)
- (2S)-piperazine-2-carboxylic acid (CAS 147650-70-2)
- 8-Bromo-6-phenylimidazo[1,2-a]pyrazine hydrobromide (CAS 84066-12-6)
- 2-((5-Amino-4-phenylthiazol-2-yl)thio)acetamide (CAS 1021223-06-2)
- 4-(Difluoromethyl)-2-iodo-3-methylpyridine (CAS 1803687-85-5)
- 3,12-Bis(2-chloroethyl)-3,6,9,12-tetraazadispiro[5.2.5(9).2(6)]Hexadecane-6,9-diium chloride (CAS 1158-80-1)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com