Bromo-PEG2-NHS ester CAS 2148295-96-7
| CAS No. | 2148295-96-7 |
| Molecular Formula | C11H16BrNO6 |
| Molecular Weight | 338.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bromo-PEG2-NHS ester.
Bromo-PEG2-NHS ester (CAS 2148295-96-7) is a high-purity analytical reference standard with the molecular formula C11H16BrNO6 and a molecular weight of 338.15 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, Bromo-PEG2-NHS ester is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 338.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Bromo-PEG2-NHS ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16BrNO6 |
| Molecular Weight | 338.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 1-Methyl-1H-pyrrolo[3,2-c]pyridine-4,6(5H,7H)-dione (CAS 501102-23-4)
- 2-(3-Chloropropyl)-6-fluoroquinazoline (CAS 2006277-67-2)
- 1-[4-(9-aminonon-1-ynyl)phenyl]hexahydropyrimidine-2,4-dione (CAS 2633725-44-5)
- Ethyl 3-bromo-1-methyl-1H-pyrazole-5-carboxylate (CAS 1211587-55-1)
- Vonoprazan Impurity 247 (CAS CATO-C4X-1020247)
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