3-Fluoro-6-nitro-2-(trifluoromethoxy)aniline CAS 2149598-58-1
| CAS No. | 2149598-58-1 |
| Molecular Formula | C7H4F4N2O3 |
| Molecular Weight | 240.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.11 g/mol gives 3-Fluoro-6-nitro-2-(trifluoromethoxy)aniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Fluoro-6-nitro-2-(trifluoromethoxy)aniline (CAS 2149598-58-1), a certified reference material (molecular formula C7H4F4N2O3, MW 240.11 g/mol) for analytical method development and quality control.
Structurally, 3-Fluoro-6-nitro-2-(trifluoromethoxy)aniline (C7H4F4N2O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 240.11 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Fluoro-6-nitro-2-(trifluoromethoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F4N2O3 |
| Molecular Weight | 240.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 5-Fluoro-2-nitro-4-(trifluoromethoxy)aniline (CAS 2366994-50-3)
- 1-Ethyl-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 2246701-92-6)
- 2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-2-en-1-one (CAS 2301976-85-0)
- 6-Fluoro-4-(trifluoromethyl)quinoline-2-carbonitrile (CAS 1116339-60-6)
- 3-Fluoro-4-((trifluoromethyl)thio)benzoic acid (CAS 1208080-44-7)
- (4-Fluoro-3-((tetrahydro-2h-pyran-2-yl)oxy)phenyl)boronic acid (CAS 1217501-17-1)
- [5-fluoro-2-(oxolan-2-ylmethoxy)phenyl]boronic acid (CAS 1310939-56-0)
- [5-fluoro-2-(oxolan-3-ylmethoxy)phenyl]boronic acid (CAS 1334327-75-1)
Recommended Standards
- 3,5-Dichloro-N-methylbenzenesulfonamide (CAS 344298-10-8)
- 4,5-Bis(trifluoromethyl)picolinonitrile (CAS 329711-41-3)
- 3,5-Dichloro-4-methylbenzene-1-sulfonamide (CAS 861518-65-2)
- 5,5-Dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane (CAS 22871-77-8)
- (S)-4-(3-Aminobutyl)phenol (CAS 74248-90-1)
- 4-(1-Isopropyl-1H-pyrazol-4-yl)-4-methoxypiperidine (CAS 1710696-09-5)
- 3,7-Diiodo-1H-indazol-6-ol (CAS 1190322-50-9)
- 3-(4-Methoxypyrimidin-2-yl)pyrazolo[1,5-a]pyridine (CAS 1330043-83-8)
- Imino(methyl)(4-nitrophenyl)-λ6-sulfanone (CAS 22133-01-3)
- 6-Chloro-3-cyclopropoxy-2-ethylpyridine (CAS 1243445-05-7)
- 1-(4-Methoxyphenyl)cyclobutanamine hydrochloride (CAS 1228879-06-8)
- (5-(Thiophen-2-yl)isoxazol-3-yl)methanamine (CAS 852180-45-1)
- 1,6-Dimethyl-1,1,2,2,3,3,4,4,5,5,6,6-dodecaphenylhexasilane (CAS 1586-77-2)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com