2-(Difluoromethyl)-3-phenoxythiophene CAS 2149598-79-6
| CAS No. | 2149598-79-6 |
| Molecular Formula | C11H8F2OS |
| Molecular Weight | 226.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(Difluoromethyl)-3-phenoxythiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(Difluoromethyl)-3-phenoxythiophene (CAS 2149598-79-6), molecular formula C11H8F2OS and molecular weight 226.24 g/mol, is a CATO reference standard with documented purity and traceability.
2-(Difluoromethyl)-3-phenoxythiophene (C11H8F2OS) contains sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H8F2OS |
| Molecular Weight | 226.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluoromethyl Standards
- 5-(5-(Difluoromethyl)thiophen-2-yl)pyridin-2-amine (CAS 2090989-65-2)
- Methyl 2-(difluoromethyl)-1H-benzo[d]imidazole-4-carboxylate (CAS 1336890-32-4)
- 2-(Difluoromethyl)-1-methyl-1h-1,3-benzodiazole-5-carboxylic acid (CAS 1339147-00-0)
- 2-(Difluoromethyl)-7-methoxy-4H-chromen-4-one (CAS 156909-18-1)
- 2-(Difluoromethyl)-3-fluoropyridine-4-sulfonamide (CAS 1804707-20-7)
- 4-(Difluoromethyl)-5-fluoropyridine-3-sulfonamide (CAS 1805308-21-7)
- 2-(Difluoromethyl)-6-fluoropyridine-3-sulfonamide (CAS 1805321-81-6)
- 4-(Difluoromethyl)-2-fluoropyridine-3-sulfonamide (CAS 1805321-94-1)
Recommended Standards
- 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine (CAS 5399-88-2)
- 2-O-Benzyl-3,5-dideoxy-3-fluoropentofuranose (CAS 786709-91-9)
- 1-Methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 91092-05-6)
- 3-Fluoro-4-(pentyloxy)benzoic acid (CAS 583-24-4)
- 3-Fluoro-4-methoxyphenyl Isothiocyanate (CAS 344750-44-3)
- tert-Butyl (R)-3-([1,1'-biphenyl]-2-yl)piperazine-1-carboxylate (CAS 1228550-21-7)
- N-(2-Ethylphenyl)-2-phenyl-2-(1H-pyrrol-1-yl)acetamide (CAS 1257546-52-3)
- 1-(Methylsulfonyl)-1,4-diazepane hydrochloride (CAS 550369-26-1)
- 6-Oxospiro[3.3]heptane-2-carbonitrile (CAS 2090030-99-0)
- Vortioxetine Impurity 28 (CAS CATO-C4X-105628)
- 4-(((1-Cyclopentyl-1H-pyrazol-4-yl)methyl)amino)butan-1-ol hydrochloride (CAS 1856082-25-1)
- Methyl 2-chloro-6-fluoroquinoline-4-carboxylate (CAS 1243032-25-8)
- 5-Hydroxyquinoxaline-2-carbaldehyde (CAS 394223-65-5)
- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
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