1-(3-Chloropyridin-4-yl)cyclopropan-1-amine hydrochloride CAS 2149601-46-5
| CAS No. | 2149601-46-5 |
| Molecular Formula | C8H9ClN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(3-Chloropyridin-4-yl)cyclopropan-1-amine hydrochloride (CAS 2149601-46-5), molecular formula C8H9ClN2HCl and molecular weight 205.08 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-Chloropyridin-4-yl)cyclopropan-1-amine hydrochloride (C8H9ClN2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-(3-Chloropyridin-4-yl)cyclopropan-1-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9ClN2 HCl |
| Molecular Weight | 205.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloropyridin Standards
- 3-(2-Chloropyridin-3-yl)propan-1-amine (CAS 1000512-13-9)
- 2-(4-chloropyridin-2-yl)acetonitrile (CAS 1000515-40-1)
- 2-(5-Chloropyridin-2-yl)acetic acid (CAS 1000522-43-9)
- 3-(6-Chloropyridin-3-yl)propan-1-amine (CAS 1000543-63-4)
- 3-(2-Chloropyridin-4-yl)propan-1-amine (CAS 1000545-70-9)
- 2-(3-Chloropyridin-4-yl)acetic acid (CAS 1000553-75-2)
- 3-(3-Chloropyridin-4-yl)propan-1-amine (CAS 1000555-79-2)
- 2-(4-Chloropyridin-3-yl)acetic acid (CAS 1000567-15-6)
Recommended Standards
- 5,5-Difluoro-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 1031926-89-2)
- Mirabijalone D (CAS 485811-84-5)
- 2-[(phenylamino)methyl]aniline (CAS 20887-06-3)
- 1-(1,1-Difluoroethyl)-3-methylbenzene (CAS 1204295-94-2)
- Methyl furo[2,3-b]pyridine-3-carboxylate (CAS 193284-85-4)
- Butanedioic acid, 1-(1,1-dimethylethyl) 4-(2,5-dioxo-1-pyrrolidinyl) ester (CAS 138833-93-9)
- (1-(3,4-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)methyl 2,2,2-trichloroacetate (CAS 338419-47-9)
- 6,6-Dimethyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, 97% (CAS 581083-30-9)
- 4-(6-Cyclopropylamino-pyrimidin-4-ylamino)-piperidine-1-carboxylic acid tert-butyl ester (CAS 1353946-67-4)
- Des-Ile27-Tirzepatide (CAS CATO-CPTD788946)
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