Methyl 3-chloro-5-methoxyisonicotinate CAS 214976-37-1
| CAS No. | 214976-37-1 |
| Molecular Formula | C8H8ClNO3 |
| Molecular Weight | 201.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 3-chloro-5-methoxyisonicotinate (CAS 214976-37-1) is a high-purity analytical reference standard with the molecular formula C8H8ClNO3 and a molecular weight of 201.61 g/mol.
Methyl 3-chloro-5-methoxyisonicotinate (C8H8ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Methyl 3-chloro-5-methoxyisonicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO3 |
| Molecular Weight | 201.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- Methyl 3,5-diamino-6-chloropicolinate (CAS 465513-11-5)
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- Ethyl 4-(6-chloropyridin-3-yl)-4-oxobutanoate (CAS 890100-63-7)
- 5-Isopropylbenzene-1,2,3-triamine (CAS 2792169-39-0)
- (E)-6,6,6-Trideuterio-4-hydroxyhex-2-enal (CAS 148706-05-2)
- Methyl 5-Chloro-2-pyrazinecarboxylate (CAS 33332-25-1)
- 6-(Cyclopropylmethoxy)pyridine-2,3-diamine (CAS 1534808-26-8)
- 4-(4-(tert-Butyl)phenoxy)-2-((4-chlorobenzyl)thio)-5-methoxypyrimidine (CAS 338423-21-5)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com