25,26,26,26,27,27,27-Heptafluoro-7-ketocholesterol CAS 215094-37-4

Purity 97%+In StockPharmaceutical Standards
CAS No.215094-37-4
Molecular FormulaC27H37F7O2
Molecular Weight526.57 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

25,26,26,26,27,27,27-Heptafluoro-7-ketocholesterol CAS 215094-37-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 526.57 g/mol gives 25,26,26,26,27,27,27-Heptafluoro-7-ketocholesterol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

25,26,26,26,27,27,27-Heptafluoro-7-ketocholesterol (CAS 215094-37-4), molecular formula C27H37F7O2 and molecular weight 526.57 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 25,26,26,26,27,27,27-Heptafluoro-7-ketocholesterol (C27H37F7O2) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC27H37F7O2
Molecular Weight526.57 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2018
Halogen ContentF-containing

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Why CATO?