4-[5-(trifluoromethyl)-1h-pyrazol-1-yl]aniline CAS 215500-56-4
| CAS No. | 215500-56-4 |
| Molecular Formula | C10H8F3N3 |
| Molecular Weight | 227.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[5-(trifluoromethyl)-1h-pyrazol-1-yl]aniline.
4-[5-(trifluoromethyl)-1h-pyrazol-1-yl]aniline (CAS 215500-56-4), molecular formula C10H8F3N3 and molecular weight 227.19 g/mol, is a CATO reference standard with documented purity and traceability.
4-[5-(trifluoromethyl)-1h-pyrazol-1-yl]aniline (C10H8F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[5-(trifluoromethyl)-1h-pyrazol-1-yl]aniline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8F3N3 |
| Molecular Weight | 227.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related trifluoromethyl Standards
- 7-(Trifluoromethyl)quinoline-3,4-diamine (CAS 110643-85-1)
- 1-(3-(Trifluoromethyl)benzyl)-1H-1,2,4-triazole (CAS 115201-44-0)
- 3-[5-(trifluoromethyl)-1h-pyrazol-1-yl]aniline (CAS 1152530-85-2)
- 1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-4-amine (CAS 1153040-21-1)
- 1-(2-(Trifluoromethyl)phenyl)-1h-pyrazol-3-amine (CAS 1248322-84-0)
- 1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-amine (CAS 1251264-73-9)
- 3-[4-(trifluoromethyl)-1h-pyrazol-1-yl]aniline (CAS 1306605-68-4)
- 1-(2-(Trifluoromethyl)phenyl)-1h-pyrazol-5-amine (CAS 1349717-35-6)
Recommended Standards
- 4-[4-(trifluoromethyl)phenyl]-1H-imidazol-2-amine (CAS 37148-87-1)
- 4-Amino-1-((2S,5S)-3-fluoro-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 405238-91-7)
- 4-[3-(trifluoromethyl)-1h-pyrazol-1-yl]aniline (CAS 231953-33-6)
- 4-Hydrazinyl-6-(trifluoromethyl)quinoline (CAS 49612-02-4)
- 5-Chloro-3-(3-(trifluoromethoxy)phenyl)pyrazolo[1,5-a]pyrimidine (CAS 1361951-79-2)
- 1-Methyl-4-phenyl-1H-pyrazole-5-carboxylic acid (CAS 142598-53-6)
- 2-(2-Piperidinyl)ethyl 2-methylpropanoate hydrochloride (CAS 1219979-79-9)
- 2-((2-Chloro-6-fluorobenzyl)thio)-4,5-diisobutyl-1-propyl-1H-imidazole (CAS 338966-20-4)
- 3-(Benzylthio)-2-methylfuran (CAS 61720-54-5)
- 4-Cyanophenyl 4-(trans-4-ethylcyclohexyl)benzoate (CAS 89331-97-5)
- 2,5-Dioxopyrrolidin-1-yl 5-((3aR,4R,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate (CAS 1245615-71-7)
- 1,3,4,5-Tetrahydrophenanthridin-6(2H)-one (CAS 80031-06-7)
- 7-Methoxy-3-methyl-2-((methylthio)amino)-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one (CAS 90065-68-2)
- Polymyxin B nonapeptide (CAS 86408-36-8)
Why CATO?
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