5-Cyclopropylpyrimidin-2-amine CAS 21573-16-0
| CAS No. | 21573-16-0 |
| Molecular Formula | C7H9N3 |
| Molecular Weight | 135.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Cyclopropylpyrimidin-2-amine.
5-Cyclopropylpyrimidin-2-amine (CAS 21573-16-0) is a high-purity analytical reference standard with the molecular formula C7H9N3 and a molecular weight of 135.17 g/mol.
Owing to a nitrile group, an aromatic ring system, 5-Cyclopropylpyrimidin-2-amine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 135.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Cyclopropylpyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9N3 |
| Molecular Weight | 135.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 3 |
Related Cyclopropylpyrimidin Standards
- 4-Cyclopropylpyrimidin-5-amine (CAS 1368221-52-6)
- N-cyclopropylpyrimidin-2-amine (CAS 151390-00-0)
- 5-Cyclopropylpyrimidin-4-amine (CAS 1849594-13-3)
- 2-Cyclopropylpyrimidin-4-amine (CAS 265324-26-3)
- 6-Cyclopropylpyrimidin-4-amine (CAS 7043-08-5)
- 4-Cyclopropylpyrimidin-2(1H)-one (CAS 1215071-65-0)
- 2-Cyclopropylpyrimidin-4-ol (CAS 74649-06-2)
- 2-cyclopropylpyrimidin-5-ol (CAS 73901-41-4)
Recommended Standards
- 5-Cyclopropylpyrazin-2-amine (CAS 920313-51-5)
- 5-Ethynyl-1,3-dimethyl-1h-pyrazol-4-amine (CAS 94990-00-8)
- 5-Allylpyrazin-2-amine (CAS 710323-25-4)
- 5-Methylpicolinimidamide (CAS 875401-87-9)
- 6-Ethyl-4,5,6,7-tetrahydro-1-benzothiophene-2-carbohydrazide (CAS 956576-53-7)
- (3-Propyloxetan-3-yl)methyl 4-iodobenzoate (CAS 118546-18-2)
- Methyl 5-(4-methoxyphenyl)-3-oxopent-4-enoate (CAS 92362-85-1)
- 2-(4-Chloropyridin-2-yl)propan-2-amine (CAS 1303968-31-1)
- 4-[(3-amino-4-bromo-1h-pyrazol-1-yl)methyl]benzohydrazide (CAS 375837-72-2)
- 4-tert-Butyl-3-ethylcyclohexan-1-one (CAS 100103-31-9)
- N,N,N-Trimethyladamantan-1-aminium hydroxide (CAS 53075-09-5)
- n-(2,3-Dimethylphenyl)-2-ethyl-3-methylquinoline-4-carboxamide (CAS 332358-67-5)
- 4-Amino-7-((2R,3S,4S,5R)-3-amino-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (CAS 127880-86-8)
- Neuropeptide EI (human, mouse, rat) (CAS 125934-45-4)
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