2,3-Dibromo-4-oxobut-2-enoic acid CAS 21577-50-4
| CAS No. | 21577-50-4 |
| Molecular Formula | C4H2Br2O3 |
| Molecular Weight | 257.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,3-Dibromo-4-oxobut-2-enoic acid (CAS 21577-50-4), molecular formula C4H2Br2O3 and molecular weight 257.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,3-Dibromo-4-oxobut-2-enoic acid (C4H2Br2O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 2,3-Dibromo-4-oxobut-2-enoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H2Br2O3 |
| Molecular Weight | 257.86 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Br-containing |
Related Dibromo Standards
- (E)-2,3-Dibromo-4-oxobut-2-enoic acid (CAS 90994-06-2)
- 3,4-Dibromo-5-hydroxyfuran-2(5H)-one (CAS 766-38-1)
- 2,5-Dibromo-4-fluoro-1-methyl-1H-imidazole (CAS 1824064-07-4)
- 1,5-Dibromo-2,4-pentanedione (CAS 68864-57-3)
- 2,2-Dibromo-1-methylcyclopropane-1-carboxylic acid (CAS 5365-21-9)
- 1,5-Dibromo-3,3-dimethylpentane (CAS 37746-17-1)
- 1,2-Dibromo-1-chloro-2,2-difluoroethane (CAS 421-36-3)
- 1,2-Dibromo-3-thiocyanatoprop-1-ene (CAS 102367-28-2)
Recommended Standards
- 2-Chloro-4-pyridylzinc bromide (CAS 1227940-97-7)
- 3,4-Dibromodihydrofuran-2,5-dione (CAS 45669-18-9)
- 2-Chloro-3-pyridylzinc bromide 0.5 M in Tetrahydrofuran (CAS 1227833-83-1)
- Mucobromic acid 2,3-dibromomalealdehydic acid (2z)-2,3-dibromo-4-oxobut-2-enoic acid 2,3-dibromo-4-oxo-2-butenoic acid dibromoaldehydoacrylic acid a,b-dibromo-b-formylacrylic acid 2,3-dibromomaleic aldehyde acid Bromomucic acid 488-11-9 (CAS 488-11-9)
- dY-V-G (CAS 86030-52-6)
- Ethyl 2-hydroxypropanimidate (CAS 57871-82-6)
- 2,5-Dimethyl-3-(2-(trifluoromethyl)-1H-imidazol-5-yl)piperazine (CAS 2366183-31-3)
- Dibenzo[b,j][4,7]phenanthroline (CAS 223-00-7)
- 3-(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-amine (CAS 93808-12-9)
- (2-(4-Methoxyphenyl)-1-methylpyrrolidin-3-yl)methanamine (CAS 1311316-38-7)
- Cefpodoxime Proxetil Impurity 9 (CAS CATO-C4X-15799)
- 1-(9H-carbazol-9-yl)-3-((2-hydroxyethyl)amino)propan-2-ol (CAS 301160-68-9)
- Methyl 2-(4-benzenesulfonamidophenoxy)benzoate (CAS 866020-30-6)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
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