tert-Butyl (2-bromo-5-chlorobenzyl)carbamate CAS 2158581-87-2
| CAS No. | 2158581-87-2 |
| Molecular Formula | C12H15BrClNO2 |
| Molecular Weight | 320.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (2-bromo-5-chlorobenzyl)carbamate.
tert-Butyl (2-bromo-5-chlorobenzyl)carbamate (CAS 2158581-87-2) is a high-purity analytical reference standard with the molecular formula C12H15BrClNO2 and a molecular weight of 320.61 g/mol.
The molecular framework of tert-Butyl (2-bromo-5-chlorobenzyl)carbamate (C12H15BrClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures tert-Butyl (2-bromo-5-chlorobenzyl)carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15BrClNO2 |
| Molecular Weight | 320.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-(2-(4-Bromo-2-chlorophenoxy)ethyl)morpholine (CAS 435285-43-1)
- tert-Butyl (4-(bromomethyl)-2-chlorophenyl)carbamate (CAS 885020-88-2)
- 4-(1-Bromoethyl)-9-chloroacridine (CAS 55816-91-6)
- Tert-butyl (4-bromo-2-chlorobenzyl)carbamate (CAS 864266-10-4)
- 4-Chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-ol (CAS 2138371-15-8)
- 4-Bromo-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 84547-84-2)
- 3-(Triethoxysilyl)propan-1-ol (CAS 53394-61-9)
- 1-(4-(Azetidin-3-yl)piperazin-1-yl)-2-methylpentan-1-one (CAS 1483636-47-0)
- 2-(4-(Difluoromethyl)-5-fluoropyridin-3-yl)acetic acid (CAS 1803666-27-4)
- 3-deuterioazetidin-3-ol (CAS 2768390-37-8)
- sodium 2-{thieno[2,3-d]pyrimidin-4-yl}acetate (CAS 1909319-92-1)
- Testosterone Impurity 38 (CAS CATO-C4X-243238)
- Lorglumide Sodium Salt (CAS 1021868-76-7)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com