8-Nitroisoquinolin-1(2H)-one CAS 216097-70-0
| CAS No. | 216097-70-0 |
| Molecular Formula | C9H6N2O3 |
| Molecular Weight | 190.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Nitroisoquinolin-1(2H)-one (C9H6N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 8-Nitroisoquinolin-1(2H)-one (CAS 216097-70-0), a certified reference material (molecular formula C9H6N2O3, MW 190.16 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6N2O3 |
| Molecular Weight | 190.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2018 |
| Nitrogen Atoms | 2 |
Related Nitroisoquinolin Standards
- 3-Nitroisoquinolin-4-ol (CAS 36718-46-4)
- 4-Nitroisoquinolin-1(2H)-one (CAS 55404-29-0)
- 4-Nitroisoquinolin-3-ol (CAS 669769-53-3)
- 5-Nitroisoquinolin-1(2H)-one (CAS 82827-08-5)
- 5-Nitroisoquinolin-3-ol (CAS 581813-27-6)
- 6-Nitroisoquinolin-1(2H)-one (CAS 928032-23-9)
- 7-Nitroisoquinolin-1(2H)-one (CAS 20141-83-7)
- 8-Nitroisoquinolin-5-amine (CAS 156901-58-5)
Recommended Standards
- 8-Nitrocinnolin-4-amine (CAS 872284-83-8)
- 8-Nitrophthalazin-5-amine (CAS 502584-69-2)
- 7-Nitroquinolin-4(1H)-one (CAS 6270-14-0)
- 8-Nitroquinolin-2(1H)-one (CAS 7461-12-3)
- Tert-butyl ((1-hydroxy-4,4-dimethylcyclohexyl)methyl)carbamate (CAS 1494390-21-4)
- 5-Iodo-1,4-dimethyl-1H-pyrazole (CAS 1420831-53-3)
- Methyl 4-Amino-3-methoxybenzoate (CAS 41608-64-4)
- Ethyl 3-bromo-8-methylimidazo[1,2-a]pyridine-2-carboxylate hydrobromide (CAS 1332589-38-4)
- Imidazo[1,2-a]pyridin-6-ylmethanol hydrochloride (CAS 1588440-93-0)
- 4-Cyano-5-cyclopropoxypicolinic acid (CAS 1243470-27-0)
- N-(5-Amino-2-fluorophenyl)-2-(pentyloxy)benzamide (CAS 1020057-31-1)
- 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)imidazo[1,5-a]pyridine (CAS 1416367-32-2)
- 1-(4-Nitrophenyl)sulfonylpyrrolidine (CAS 175278-37-2)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
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