(R)-5-(((tert-butyldimethylsilyl)oxy)methyl)morpholin-3-one CAS 2165661-27-6
| CAS No. | 2165661-27-6 |
| Molecular Formula | C11H23NO3Si |
| Molecular Weight | 245.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (R)-5-(((tert-butyldimethylsilyl)oxy)methyl)morpholin-3-one (C11H23NO3Si) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(R)-5-(((tert-butyldimethylsilyl)oxy)methyl)morpholin-3-one (CAS 2165661-27-6) is a high-purity analytical reference standard with the molecular formula C11H23NO3Si and a molecular weight of 245.39 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-5-(((tert-butyldimethylsilyl)oxy)methyl)morpholin-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H23NO3Si |
| Molecular Weight | 245.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (R)-6-(((tert-butyldimethylsilyl)oxy)methyl)morpholin-3-one (CAS 1885891-00-8)
- (S)-5-(((tert-butyldimethylsilyl)oxy)methyl)morpholin-3-one (CAS 2165838-75-3)
- 5-(2-((tert-Butyldimethylsilyl)oxy)ethyl)oxazolidin-2-one (CAS 1184303-40-9)
- 2-(Trimethylsilyl)ethyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 2413671-61-9)
- 4-Chloro-5-nitro-1H-pyrazolo[3,4-b]pyridine (CAS 1638769-09-1)
- 2-[5-(chloromethyl)-1,2,4-oxadiazol-3-yl]-N-methylacetamide (CAS 1384430-49-2)
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- 1-[3-(2,2-difluoroethyl)piperidin-1-yl]-2-{1H-pyrrolo[2,3-b]pyridin-3-yl}ethan-1-one (CAS 2813202-36-5)
- (2-Amino-5-(difluoromethyl)-4-methylpyridin-3-yl)methanol (CAS 1805016-92-5)
- 1-His-N-a-ethylidene Semaglutide (CAS CATO-C4X-2226252)
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