(1S,5S,6S)-2,2-difluorobicyclo[3.1.0]Hexane-6-carboxylic acid CAS 2165698-45-1
| CAS No. | 2165698-45-1 |
| Molecular Formula | C7H8F2O2 |
| Molecular Weight | 162.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(1S,5S,6S)-2,2-difluorobicyclo[3.1.0]Hexane-6-carboxylic acid (CAS 2165698-45-1), molecular formula C7H8F2O2 and molecular weight 162.13 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (1S,5S,6S)-2,2-difluorobicyclo[3.1.0]Hexane-6-carboxylic acid (C7H8F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 162.13 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1S,5S,6S)-2,2-difluorobicyclo[3.1.0]Hexane-6-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8F2O2 |
| Molecular Weight | 162.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Recommended Standards
- 1,1-difluorospiro[2.3]hexane-5-carboxylic acid (CAS 1955514-17-6)
- 1-Cyclopropyl-4,4-difluorobutane-1,3-dione (CAS 758709-39-6)
- 2,2-Difluorospiro[2.3]Hexane-1-carboxylic acid (CAS 1936230-67-9)
- 2-(2,2-Difluoroacetyl)cyclopentan-1-one (CAS 938001-14-0)
- Ethyl 2-(3-chlorophenyl)ethanimidate hydrochloride (CAS 103754-13-8)
- 4-Chloro-2-fluoro-6-methoxybenzamide (CAS 1823882-44-5)
- 2-[2-(4-Nitro-1h-pyrazol-1-yl)ethyl]-2,3-dihydro-1h-isoindole-1,3-dione (CAS 1240574-51-9)
- 4-((9H-Fluoren-9-ylidene)amino)phenol (CAS 58633-11-7)
- LB-100 (CAS 1632032-53-1)
- 2-(3-Fluorophenyl)pyrrolidine (CAS 298690-72-9)
- N-(4-Iodophenyl)-2,2-diphenylacetamide (CAS 70298-75-8)
- (1S,3R,4S,6R)-N-BOc-6-amino-2,2-dimethyltetrahydrocyclopenta[1.3]dioxole-4-carb acid (CAS 220497-93-8)
- Ethyl 2-amino-5-iodobenzoate (CAS 268568-11-2)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
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