(3S,4R)-3-fluoropiperidine-4-carboxylic acid CAS 2166219-99-2
| CAS No. | 2166219-99-2 |
| Molecular Formula | C6H10FNO2 |
| Molecular Weight | 147.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (3S,4R)-3-fluoropiperidine-4-carboxylic acid (CAS 2166219-99-2), a certified reference material (molecular formula C6H10FNO2, MW 147.15 g/mol) for analytical method development and quality control.
The molecular framework of (3S,4R)-3-fluoropiperidine-4-carboxylic acid (C6H10FNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3S,4R)-3-fluoropiperidine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10FNO2 |
| Molecular Weight | 147.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,5R)-5-Fluoropiperidine-2-carboxylic acid (CAS 675605-36-4)
- (E)-3-(4-Fluorophenyl)acrylonitrile (CAS 24654-48-6)
- (2S,4S)-4-Fluoropiperidine-2-carboxylic acid (CAS 403503-52-6)
- (R)-3-Fluoropiperidine-3-carboxylic acid (CAS 211379-83-8)
- 3,5-Bis(ethoxycarbonyl)-1H-pyrrole-2-carboxylic acid (CAS 1221742-35-3)
- 2-[(4-Fluorobenzyl)amino]nicotinonitrile (CAS 854382-09-5)
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