Tert-butyl (R)-3-(2,2,2-trifluoro-1-hydroxyethyl)azetidine-1-carboxylate CAS 2166273-43-2

Purity 97%+In StockPharmaceutical Standards
CAS No.2166273-43-2
Molecular FormulaC10H16F3NO3
Molecular Weight255.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl (R)-3-(2,2,2-trifluoro-1-hydroxyethyl)azetidine-1-carboxylate CAS 2166273-43-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 255.23 g/mol gives Tert-butyl (R)-3-(2,2,2-trifluoro-1-hydroxyethyl)azetidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Tert-butyl (R)-3-(2,2,2-trifluoro-1-hydroxyethyl)azetidine-1-carboxylate (CAS 2166273-43-2), molecular formula C10H16F3NO3 and molecular weight 255.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Tert-butyl (R)-3-(2,2,2-trifluoro-1-hydroxyethyl)azetidine-1-carboxylate (C10H16F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures Tert-butyl (R)-3-(2,2,2-trifluoro-1-hydroxyethyl)azetidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H16F3NO3
Molecular Weight255.23 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1998
Halogen ContentF-containing
Nitrogen Atoms1

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