1-Ethynyl-3-methyl-5-(trifluoromethyl)benzene CAS 2166730-36-3
| CAS No. | 2166730-36-3 |
| Molecular Formula | C10H7F3 |
| Molecular Weight | 184.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Ethynyl-3-methyl-5-(trifluoromethyl)benzene (CAS 2166730-36-3), molecular formula C10H7F3 and molecular weight 184.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine substitution, an aromatic ring system, 1-Ethynyl-3-methyl-5-(trifluoromethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1-Ethynyl-3-methyl-5-(trifluoromethyl)benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F3 |
| Molecular Weight | 184.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
Related Ethynyl Standards
- 2-Ethynyl-1-methyl-4-(trifluoromethyl)benzene (CAS 121793-11-1)
- 4-Ethynyl-1-methyl-2-(trifluoromethyl)benzene (CAS 1343862-48-5)
- 1-Ethynyl-2-methyl-3-(trifluoromethyl)benzene (CAS 2029239-28-7)
- 2-Ethynyl-5-phenylthiophene (CAS 1665-35-6)
- 5-Ethynyl-6-methoxyquinoline (CAS 1420790-19-7)
- 5-Ethynyl-2-(trifluoromethyl)aniline (CAS 1233512-89-4)
- 4-Ethynyl-2-(trifluoromethyl)aniline (CAS 1233517-89-9)
- 4-Ethynyl-3-(trifluoromethyl)aniline (CAS 1260677-91-5)
Recommended Standards
- 1H-imidazole-4,5-dicarbohydrazide (CAS 5423-20-1)
- 1-(Prop-2-yn-1-yl)-3-(trifluoromethyl)benzene (CAS 67396-33-2)
- 1-Methyl-4-(trifluoroprop-1-yn-1-yl)benzene (CAS 82203-82-5)
- (S)-2-(4-Fluorophenoxy)propanoic acid (CAS 60251-91-4)
- 1-((2-Methoxypyridin-4-yl)methyl)guanidine (CAS 1275393-33-3)
- Trichloro Bisphenol S (CAS 80396-78-7)
- 2-Cyanothiazole-4-carboxylic acid (CAS 1211527-90-0)
- 7-Amino-3,4,6-trimethylquinolin-2(1H)-one (CAS 847985-41-5)
- (4-Chloro-3-methylthiophen-2-yl)(phenyl)methanol (CAS 1443326-91-7)
- 5-aminothiophene-2-carbonitrile (CAS 52532-63-5)
- 1-(4-Amino-3-methylphenoxy)propan-2-ol (CAS 1138140-83-6)
- 2-(Pyrrolidin-2-yl)-1,3-oxazole (CAS 1313729-35-9)
- 2-Phenylbenzo[cd]indol-5(1H)-one (CAS 75528-57-3)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com