tert-Butyl 3-ethynyl-3-methoxypyrrolidine-1-carboxylate CAS 2167159-22-8
| CAS No. | 2167159-22-8 |
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, tert-Butyl 3-ethynyl-3-methoxypyrrolidine-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 225.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies tert-Butyl 3-ethynyl-3-methoxypyrrolidine-1-carboxylate (CAS 2167159-22-8), a certified reference material (molecular formula C12H19NO3, MW 225.28 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), tert-Butyl 3-ethynyl-3-methoxypyrrolidine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Recommended Standards
- tert-butyl 3-ethynyl-3-hydroxypiperidine-1-carboxylate (CAS 287192-85-2)
- tert-Butyl 3-oxo-2-azabicyclo[2.2.2]octane-2-carboxylate (CAS 2007916-87-0)
- Tert-butyl 3-(3-oxocyclobutyl)azetidine-1-carboxylate (CAS 2167190-21-6)
- tert-Butyl 3-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate (CAS 359779-74-1)
- (3-(tert-Butoxy)pyridin-4-yl)methanamine (CAS 1500377-36-5)
- 3-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-3-yl}-1-(4-chlorophenyl)-1,4-dihydropyridazin-4-one (CAS 318498-11-2)
- 3-(Trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 223915-99-9)
- 2-(1-Methylpyrrolidin-3-yl)acetic acid (CAS 102014-77-7)
- Ethyl 2-(methylthio)nicotinate (CAS 91540-68-0)
- 1-(6-Methoxy-2-methylpyridin-3-yl)-N-methylmethanamine (CAS 1355182-72-7)
- (E)-5-methyl-4-(4-nitrobenzylidene)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (CAS 132603-48-6)
- tert-Butyl N-(3-chlorophenyl)-N-ethylcarbamate (CAS 1881290-62-5)
- (2E)-1,3-Bis(2-methoxyphenyl)prop-2-en-1-one (CAS 105473-08-3)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
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