1-Bromo-2-(difluoromethoxy)-4-fluoro-5-methylbenzene CAS 2167304-78-9
| CAS No. | 2167304-78-9 |
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Bromo-2-(difluoromethoxy)-4-fluoro-5-methylbenzene (C8H6BrF3O) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-Bromo-2-(difluoromethoxy)-4-fluoro-5-methylbenzene (CAS 2167304-78-9) is a high-purity analytical reference standard with the molecular formula C8H6BrF3O and a molecular weight of 255.03 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Bromo-2-(difluoromethoxy)-4-fluoro-5-methylbenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6BrF3O |
| Molecular Weight | 255.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene (CAS 106854-77-7)
- (2-Bromo-3-(trifluoromethyl)phenyl)methanol (CAS 1214330-94-5)
- 1-Bromo-3-methoxy-2-(trifluoromethyl)benzene (CAS 1214345-25-1)
- (5-Bromo-2-(trifluoromethyl)phenyl)methanol (CAS 1214349-54-8)
- (2-Bromo-6-(trifluoromethyl)phenyl)methanol (CAS 1214350-24-9)
- 4-Bromo-1-methoxy-2-(trifluoromethyl)benzene (CAS 1514-11-0)
- 1-Bromo-3-(2,2-difluoroethoxy)-5-fluorobenzene (CAS 1538752-02-1)
- (3-Bromo-5-(trifluoromethyl)phenyl)methanol (CAS 172023-97-1)
Recommended Standards
- 1-Bromo-2-(2,2,2-trifluoroethoxy)benzene (CAS 218610-57-2)
- 1-Bromo-2-(difluoromethyl)-3-fluoro-4-methoxybenzene (CAS 2092668-52-3)
- 1-(4-Bromophenyl)-2,2,2-trifluoroethanol (CAS 76911-73-4)
- 1-Bromo-2-methoxy-3-(trifluoromethyl)benzene (CAS 871352-91-9)
- 2-Isopropoxy-N-(4-isopropoxybenzyl)aniline (CAS 1040683-37-1)
- Benzyl (R)-2-cyanopyrrolidine-1-carboxylate (CAS 620601-77-6)
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Why CATO?
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