3-Bromo-5-chloro-4-(trifluoromethoxy)phenol CAS 2168431-40-9
| CAS No. | 2168431-40-9 |
| Molecular Formula | C7H3BrClF3O2 |
| Molecular Weight | 291.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Bromo-5-chloro-4-(trifluoromethoxy)phenol (CAS 2168431-40-9) is a high-purity analytical reference standard with the molecular formula C7H3BrClF3O2 and a molecular weight of 291.45 g/mol.
The molecular framework of 3-Bromo-5-chloro-4-(trifluoromethoxy)phenol (C7H3BrClF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H3BrClF3O2 |
| Molecular Weight | 291.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl/Br-containing |
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- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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