7-bromo-2,4-dichloro-8-fluoro-quinazoline CAS 2168499-15-6
| CAS No. | 2168499-15-6 |
| Molecular Formula | C8H12BrCl2FN2 |
| Molecular Weight | 306.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-bromo-2,4-dichloro-8-fluoro-quinazoline is closely related to a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-bromo-2,4-dichloro-8-fluoro-quinazoline (CAS 2168499-15-6) is a high-purity analytical reference standard with the molecular formula C8H12BrCl2FN2 and a molecular weight of 306.00 g/mol.
Owing to a nitrile group, fluorine/chlorine/bromine substitution, 7-bromo-2,4-dichloro-8-fluoro-quinazoline is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 306.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-bromo-2,4-dichloro-8-fluoro-quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12BrCl2FN2 |
| Molecular Weight | 306.00 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related bromo Standards
- 7-bromo-2,4-dichloro-6-fluoro-quinazoline (CAS 1374208-44-2)
- 7-bromo-4,6-dichloro-8-fluoroquinazoline (CAS 1698027-19-8)
- 2-bromo-7,8-dichloro-3-fluoro-1,5-naphthyridine (CAS 2074703-06-1)
- 8-bromo-2,4-dichloro-6-fluoro-quinazoline (CAS 864292-32-0)
- 2-Bromo-1-(2-bromo-4,6-dimethylphenyl)ethan-1-one (CAS 1246471-30-6)
- 3-Bromo-4-(2-bromophenyl)butan-2-one (CAS 1247825-43-9)
- 4-Bromo-3-(2,4-dichlorophenyl)-1-methyl-1H-pyrazole (CAS 133112-51-3)
- 7-bromo-5-(2-bromoethyl)-2,3-dihydroBenzofuran (CAS 1391080-45-7)
Recommended Standards
- 1-Fluoro-2-iodo-3-trifluoromethoxy-benzene (CAS 866632-57-7)
- tert-butyl 4,4,5,5-tetrachlorospiro[2.2]pentane-1-carboxylate (CAS 119060-44-5)
- 1-Fluoro-2-iodo-4-(trifluoromethoxy)benzene (CAS 1806432-05-2)
- Bis(p-chlorophenyl)dichloromethane (CAS 7457-25-2)
- 4-Bromo-3-fluoro-N,N-dimethylaniline (CAS 1352218-99-5)
- 2-(3,4-Dimethoxybenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (CAS 290835-37-9)
- 13-(3,4-Dimethylphenyl)-11-methyl-1,8-diazatricyclo[7.4.0.0,2,7]trideca-2,4,6,8,10,12-hexaene-10-carbonitrile (CAS 730997-93-0)
- Atrasentan Impurity 104 (CAS 1059052-11-7)
- Ethyl 2-amino-4-(3,4-dimethylphenyl)-5-methylthiophene-3-carboxylate (CAS 438220-53-2)
- Centanafadine Impurity 1 (CAS 923982-67-6)
- α-Cyano-α,β-diethylvaleric Acid Ethyl Ester (CAS 854879-12-2)
- Trimethyl cyclopropane-1,2,3-tricarboxylate (CAS 68198-35-6)
- 3-Bromo-5-bromomethyl-isoxazole (CAS 88982-28-9)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com