(4-Fluoro-3-methylphenyl)hydrazine hydrochloride CAS 21686-17-9
| CAS No. | 21686-17-9 |
| Molecular Formula | C7H9FN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (4-Fluoro-3-methylphenyl)hydrazine hydrochloride (C7H9FN2HCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies (4-Fluoro-3-methylphenyl)hydrazine hydrochloride (CAS 21686-17-9), a certified reference material (molecular formula C7H9FN2HCl, MW 176.62 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H9FN2 HCl |
| Molecular Weight | 176.62 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- 8-Hydroxy-2-methyl-1,2-dihydrophthalazin-1-one (CAS 2060047-92-7)
- Ethyl [1,2,4]triazolo[4,3-a]pyridine-8-carboxylate (CAS 1394306-53-6)
- methyl pyrazolo[1,5-a]pyrazine-3-carboxylate (CAS 53902-64-0)
- Fluorine (CAS 7782-41-4)
- 2-(3-Ethyl-2,4-dioxo-3,4-dihydropyrido[2,3-d]pyrimidin-1(2H)-yl)acetic acid (CAS 1713461-77-8)
- 2-((3-Oxo-2-(3,4,5-trimethoxybenzylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetic acid (CAS 859662-11-6)
- 2-Methoxy-5-methyl-4-(piperidin-3-yl)pyrimidine (CAS 1207174-94-4)
- Octaverine hydrochloride (CAS 6775-26-4)
- 3-Oxo-n-[2-(propan-2-yl)phenyl]butanamide (CAS 176912-27-9)
- 263251-78-1 NMG938VJ6T D-3 Tavilermide [USAN:INN] UNII-NMG938VJ6T MIM-D3 MIM-D 3 D 3 (peptide) Tavilermide (CAS 263251-78-1)
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