6-chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid CAS 2168645-49-4
| CAS No. | 2168645-49-4 |
| Molecular Formula | C8H14ClN3O2 |
| Molecular Weight | 219.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid (CAS 2168645-49-4) is a high-purity analytical reference standard with the molecular formula C8H14ClN3O2 and a molecular weight of 219.67 g/mol.
6-chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid (C8H14ClN3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-chloro-1-methyl-1H-pyrazolo[4,3-c]pyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H14ClN3O2 |
| Molecular Weight | 219.67 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
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- 6-Chloro-N-methyl-2-phenylpyrimidin-4-amine (CAS 1017782-49-8)
- 3-chloro-4-cyclopropyl-5-phenyl-4H-1,2,4-triazole (CAS 1020035-36-2)
- 2-Chloro-3-(quinolin-6-yl)propanal (CAS 1029714-85-9)
- 6-Chloro-N-(p-tolyl)pyrazin-2(1h)-imine (CAS 1030187-29-1)
- 4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid (CAS 1069473-61-5)
- 3-Chloro-N-cyclopropylquinoxalin-2-amine (CAS 1146080-50-3)
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Recommended Standards
- 6-(4-Chlorophenyl)-4-methylpyridin-2-ol (CAS 242813-30-5)
- 6-Chloro-1-methyl-3-phenylpyridin-2(1H)-one (CAS 67970-91-6)
- 6-(4-Chlorophenyl)-2-methylpyrimidin-4-amine (CAS 91349-35-8)
- 6-Chloro-1-methyl-4-phenyl-2(1H)-pyridinone (CAS 25297-57-8)
- 6-Bromo-2-oxindole (CAS 99365-40-9)
- 3-(1-Methyl-1h-pyrazol-4-yl)thiophene-2-carboxylic acid (CAS 1341908-32-4)
- 3-Chloro-N-(4-chloro-2-methylphenyl)benzamide (CAS 116681-98-2)
- (S)-2-Amino-N-((1-benzylpiperidin-4-yl)methyl)propanamide (CAS 1353995-50-2)
- (7-Diethylaminocoumarin-3-yl)carbonyl-Amyloid β-Protein (1-40) trifluoroacetate salt (CAS 1802087-66-6)
- n-[4-(2-chloropropanoyl)phenyl]-2-methylpropanamide (CAS 851398-75-9)
- 5-Amino-1-(4-chloro-2-fluorophenyl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 2197063-20-8)
- 5-(2-(Trifluoromethoxy)phenyl)pyridin-3-amine (CAS 1258620-51-7)
- 2-Oxiranecarboxylic acid, 3-phenyl-, methyl ester, (2S,3S)- (CAS 115794-68-8)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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