3-Hydroxy-2-methoxybenzoic acid CAS 2169-28-0
| CAS No. | 2169-28-0 |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Hydroxy-2-methoxybenzoic acid (C8H8O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-Hydroxy-2-methoxybenzoic acid (CAS 2169-28-0), a certified reference material (molecular formula C8H8O4, MW 168.15 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Hydroxy-2-methoxybenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Hydroxy Standards
- 3-Hydroxy-5,6-dimethylpyridazine-4-carboxylic acid (CAS 101861-29-4)
- 2-Hydroxy-4-(hydroxymethyl)benzoic acid (CAS 106420-93-3)
- 1-(5-Hydroxy-6-methoxypyridazin-4-yl)ethanone (CAS 106584-74-1)
- Methyl 4-Hydroxy-6-methylpyrimidine-2-carboxylate (CAS 1240600-77-4)
- (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetic acid (CAS 13244-75-2)
- Methyl 2-hydroxy-2-(pyrazin-2-yl)acetate (CAS 1479997-67-5)
- Methyl 2-hydroxy-2-(pyrimidin-5-yl)acetate (CAS 1494496-35-3)
- 4-Hydroxy-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carboxylic acid (CAS 1516650-68-2)
Recommended Standards
- 3-Ethyl-4-nitropyridine 1-oxide (CAS 35363-12-3)
- 3-Hydroxy-4-(hydroxymethyl)benzoic acid (CAS 74020-82-9)
- 3-Ethoxy-2-nitropyridine (CAS 74037-50-6)
- 3-Methoxy-2-methyl-6-nitropyridine (CAS 23904-02-1)
- 1-(4-(4-Chlorophenoxy)phenyl)thiourea (CAS 237385-62-5)
- 3-butoxybenzonitrile (CAS 92367-52-7)
- 4-(4-Methylpiperidin-1-yl)-1,3,5-triazin-2-amine (CAS 928711-30-2)
- 1-(Thiophen-3-yl)propan-1-one (CAS 51179-52-3)
- Prednisone-d8 (CAS CATO-C4X-191927)
- N-(2-Bromo-4-methylphenyl)-2-((4-ethyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 482639-70-3)
- 1,2-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole (CAS 2223050-13-1)
- 2-Bromo-4-(diethoxymethyl)pyridine (CAS 737000-79-2)
- 3-Bromo-4-chloro-5,7-difluoroquinoline (CAS 1204811-88-0)
- [Ser39-OH] Tirzepatide (CAS CATO-C4X-324041)
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