Ethyl (Z)-3-(4-Chlorophenyl)-2-cyanoacrylate CAS 2169-68-8

Purity 97%+In StockPharmaceutical Standards
CAS No.2169-68-8
Molecular FormulaC12H10ClNO2
Molecular Weight235.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl (Z)-3-(4-Chlorophenyl)-2-cyanoacrylate CAS 2169-68-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 235.67 g/mol gives Ethyl (Z)-3-(4-Chlorophenyl)-2-cyanoacrylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ethyl (Z)-3-(4-Chlorophenyl)-2-cyanoacrylate (CAS 2169-68-8), molecular formula C12H10ClNO2 and molecular weight 235.67 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Ethyl (Z)-3-(4-Chlorophenyl)-2-cyanoacrylate (C12H10ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Ethyl (Z)-3-(4-Chlorophenyl)-2-cyanoacrylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC12H10ClNO2
Molecular Weight235.67 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing
Nitrogen Atoms1

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