2-((4-(2,7-Diazaspiro[3.5]nonan-2-yl)pyrimidin-5-yl)oxy)-N-ethyl-5-fluoro-N-isopropylbenzamide CAS 2169920-03-8
| CAS No. | 2169920-03-8 |
| Molecular Formula | C23H30FN5O2 |
| Molecular Weight | 427.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((4-(2,7-Diazaspiro[3.5]nonan-2-yl)pyrimidin-5-yl)oxy)-N-ethyl-5-fluoro-N-isopropylbenzamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((4-(2,7-Diazaspiro[3.5]nonan-2-yl)pyrimidin-5-yl)oxy)-N-ethyl-5-fluoro-N-isopropylbenzamide (CAS 2169920-03-8), molecular formula C23H30FN5O2 and molecular weight 427.52 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((4-(2,7-Diazaspiro[3.5]nonan-2-yl)pyrimidin-5-yl)oxy)-N-ethyl-5-fluoro-N-isopropylbenzamide (C23H30FN5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H30FN5O2 |
| Molecular Weight | 427.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Diazaspiro Standards
- 2,8-Diazaspiro[4.5]decane-8-carboxylic acid, 2-[(4-bromophenyl)methyl]-1-oxo-, 1,1-dimethylethyl ester (CAS 832710-55-1)
- 2,8-Diazaspiro[4.5]decane-2,8-dicarboxylic acid, 2-(1,1-dimethylethyl) 8-(phenylmethyl) ester (CAS 929301-98-4)
- 1-Methyl-1,8-diazaspiro[4.5]decan-2-onehydrochloride (CAS 1448855-28-4)
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- Benzyl 3,9-diazaspiro[5.6]Dodecane-3-carboxylate (CAS 2386706-08-5)
Recommended Standards
- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 332376-19-9)
- 2-(4-Oxo-5-((1-phenyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-3-yl)acetic acid (CAS 623934-95-2)
- Methyl N-Biotinyl-6-amino-2-naphthonate, 96% (CAS 1041143-49-0)
- 5-(3-(1H-Pyrrol-1-yl)-4-(m-tolyl)thiophen-2-yl)-3-(4-ethoxyphenyl)-1,2,4-oxadiazole (CAS 950266-00-9)
- 2-Amino-N-(4-(N-cyclopropylacetamido)cyclohexyl)acetamide (CAS 1353946-23-2)
- 6-Fluoroquinoxaline-2-carbaldehyde (CAS 311346-81-3)
- 3-[3-(Benzyloxy)thiophen-2-yl]-1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}urea (CAS 303147-90-2)
- 2-{[(5-methylfuran-2-yl)methyl]amino}ethan-1-ol (CAS 22099-62-3)
- 1-{4',4'-dimethyl-3',4'-dihydro-2'h-spiro[cyclopropane-1,1'-naphthalen]-2-yl}methanamine hydrochloride (CAS 1432679-84-9)
- 1-Benzyl-4-(2-bromopyridin-3-yl)piperazine (CAS 1713163-35-9)
- n-(1-Methoxybutan-2-yl)pyridin-2-amine (CAS 1481399-20-5)
- Calcium 4-carboxy-2-oxobutanoate (CAS 86248-59-1)
- 6-[(2r)-1-hydroxy-3-methylbutan-2-yl]-5h,6h,7h-pyrrolo[3,4-b]pyridin-5-one (CAS 1268952-43-7)
- PACAP-Related Peptide (PRP), rat (CAS 132769-35-8)
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