1-(3,4-Dichlorophenyl)biguanide, HCl CAS 21703-08-2
| CAS No. | 21703-08-2 |
| Molecular Formula | C8H9Cl2N5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(3,4-Dichlorophenyl)biguanide, HCl (CAS 21703-08-2), a certified reference material (molecular formula C8H9Cl2N5HCl, MW 282.55 g/mol) for analytical method development and quality control.
Structurally, 1-(3,4-Dichlorophenyl)biguanide, HCl (C8H9Cl2N5HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 282.55 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9Cl2N5 HCl |
| Molecular Weight | 282.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Dichlorophenyl Standards
- 3-(2,5-Dichlorophenyl)propan-1-ol (CAS 1000529-99-6)
- 2-(2,4-Dichlorophenyl)-5-(4-nitrophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000571-77-6)
- 1-(2,4-Dichlorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-29-1)
- 1-(3,4-Dichlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-88-5)
- 1-(3,5-Dichlorophenyl)-N,N-dimethyl-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000574-30-0)
- 2-(2,4-Dichlorophenyl)-5-(3-nitrophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 1000575-62-1)
- Ethyl 1-(3,5-dichlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-61-3)
- Ethyl 1-(3,4-dichlorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-77-1)
Recommended Standards
- 2-Bromo-3-cyclopropoxy-6-fluoropyridine (CAS 1243469-78-4)
- Dicyclohexyl(2-((Diphenylphosphino)methyl)benzyl)phosphine (CAS 850894-39-2)
- 1060817-53-9 8296AC C8H5F2NO3 [(3,5-Difluorophenyl)amino](oxo)acetic acid (CAS 1060817-53-9)
- 4-Chloro-6-(2,2-difluoropropyl)thieno[2,3-d]pyrimidine (CAS 2180956-71-0)
- 2-Bromo-1-(fluoromethyl)-3-nitrobenzene (CAS 2244083-36-9)
- 5-Norbornene-2-acetic acid succinimidyl ester (CAS 1234203-45-2)
- 5-Ethoxy-2-nitro-N-propylaniline (CAS 1437794-86-9)
- 2-(Cyclopropylmethoxy)-5-methylaniline (CAS 1094717-64-2)
- 5-Hydroxy-4-(5-(pyrrolidin-1-ylmethyl)thiophen-2-yl)isoquinolin-1(2H)-one (CAS 651030-26-1)
- Tirzepatide Impurity 48 (CAS CATO-C4X-324048)
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