rel-[(3R,4R)-4-(Trifluoromethyl)pyrrolidin-3-yl]methanol CAS 217096-42-9
| CAS No. | 217096-42-9 |
| Molecular Formula | C6H10F3NO |
| Molecular Weight | 169.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
rel-[(3R,4R)-4-(Trifluoromethyl)pyrrolidin-3-yl]methanol (CAS 217096-42-9), molecular formula C6H10F3NO and molecular weight 169.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of rel-[(3R,4R)-4-(Trifluoromethyl)pyrrolidin-3-yl]methanol (C6H10F3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), rel-[(3R,4R)-4-(Trifluoromethyl)pyrrolidin-3-yl]methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10F3NO |
| Molecular Weight | 169.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- rel-(3R,4S)-1-Methyl-4-(trifluoromethyl)pyrrolidin-3-ol (CAS 2368911-17-3)
- 2-Hydroxy-4-(trifluoromethyl)pyridine 4-trifluoromethyl-pyridin-2-ol 4-trifluoromethyl-2(1h)pyridinone 4-(trifluoromethyl)pyridin-2(1h)-one 2-hydroxy-4-trifluoromethylpyridine 4-(Trifluoromethyl)pyridin-2-ol 50650-59-4 (CAS 50650-59-4)
- rel-(2S,4R)-2-(Trifluoromethyl)piperidin-4-ol (CAS 911298-14-1)
- 2,6-diamino-1-methyl-5-nitrosopyrimidin-4(1H)-one 58160-46-6 (CAS 58160-46-6)
- a-Me-Phe(4-Ph)-OH·H2O (CAS 1231709-24-2)
- 5-(Azepan-2-yl)pentan-1-amine (CAS 20779-11-7)
- 2-Chloro-4-(4-nitrophenoxy)pyrimidine (CAS 630126-02-2)
- 4-[3-(2-chloroacetyl)-2,5-dimethyl-1h-pyrrol-1-yl]benzene-1-sulfonamide (CAS 785792-42-9)
- (E)-3-(4-Chloro-3-nitrophenyl)-N-[2-(1H-indol-3-yl)ethyl]-2-propenamide (CAS 1025276-57-6)
- 2-((4-Methylcyclohexyl)amino)butan-1-ol (CAS 1152687-93-8)
- Methyl (2E)-3-(2,5-dimethylphenyl)prop-2-enoate (CAS 199393-24-3)
- methyl 5,5-difluoro-4-oxo-1,6-dihydrocyclopenta[b]pyrrole-2-carboxylate (CAS 1041430-63-0)
- (S)-(+)-2-Amino-1-butanol (CAS 5856-62-2)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
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