7-Bromo-3-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-6-carbonitrile CAS 2173193-94-5
| CAS No. | 2173193-94-5 |
| Molecular Formula | C20H19BrClF3N4OSi |
| Molecular Weight | 531.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-Bromo-3-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-6-carbonitrile is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-Bromo-3-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-6-carbonitrile (CAS 2173193-94-5), molecular formula C20H19BrClF3N4OSi and molecular weight 531.83 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Bromo-3-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-6-carbonitrile (C20H19BrClF3N4OSi) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-Bromo-3-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indole-6-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H19BrClF3N4OSi |
| Molecular Weight | 531.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 4 |
Related Bromo Standards
- 3-Bromo-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(((4-chlorophenyl)thio)methyl)-1H-indole (CAS 339110-76-8)
- 4-Bromo-N-[(5-{[(4-bromophenyl)methyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)methyl]benzene-1-sulfonamide (CAS 338421-61-7)
- 3-((4-Bromo-2,6-difluorobenzyl)oxy)-5-(3-(4-(pyrrolidin-1-yl)butyl)ureido)isothiazole-4-carboxamide (CAS 252003-65-9)
- 3-(7-Bromo-9,9-dimethyl-9H-fluoren-2-yl)-9-(4-fluorophenyl)-9H-carbazole (CAS 1207176-72-4)
- (E)-4-Bromo-3-(1,2-dibromododec-1-en-1-yl)cinnoline (CAS 1204213-40-0)
- 5'-Bromo-3,3'',5,5''-tetra-tert-butyl-1,1':3',1''-terphenyl (CAS 120046-02-8)
- 5-Bromo-3-(2-nitrovinyl)-1H-indole (CAS 25217-77-0)
- 2-((5-(5-Bromo-2-hydroxyphenyl)-4-(2,4-dimethylphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyanophenyl)acetamide (CAS 875006-54-5)
Recommended Standards
- 2-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethyl 2-(((dodecylthio)carbonothioyl)thio)-2-methylpropanoate (CAS 1050217-24-7)
- 12-((5-Chloro-7-iodoquinolin-8-yl)oxy)dodecyl acetate (CAS 88350-17-8)
- Nizatidine EP Impurity G (CAS 1193434-63-7)
- N-(3-chloro-4-(2,6-dinitro-4-(trifluoromethyl)phenoxy)phenyl)-4-methylbenzenesulfonamide (CAS 338413-12-0)
- 1-(prop-2-en-1-yl)imidazolidin-2-one (CAS 37732-87-9)
- N’-hydroxy-2-[2-(4-methoxyphenyl)-1,3-oxazol-4-yl]ethanimidamide (CAS 950029-01-3)
- 3-(2-Chloropropanoyl)-1-(propan-2-yl)urea (CAS 879319-32-1)
- 4-Methyl-6-(methylamino)-5-nitropyrimidin-2(1H)-one (CAS 5177-15-1)
- Methyl 6-bromoimidazo[1,2-a]pyridine-8-carboxylate hydrochloride (CAS 1332581-63-1)
- methyl 1-benzyl-3-formyl-6-methyl-1H-indole-2-carboxylate (CAS 1170477-28-7)
- Methyl 4-isopropyl-2-oxopyrrolidine-3-carboxylate (CAS 80036-60-8)
- N-(4-Methylbenzyl)pyrrolidin-3-amine hydrochloride (CAS 1353973-80-4)
- 5-((4-Propoxyphenoxy)methyl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 860784-36-7)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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