Clopidogrel Impurity 83 CAS 2173294-65-8
| CAS No. | 2173294-65-8 |
| Molecular Formula | C17H16Cl2N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Clopidogrel Impurity 83.
CATO supplies Clopidogrel Impurity 83 (CAS 2173294-65-8), a pharmacopoeial impurity reference standard (molecular formula C17H16Cl2N2O3HCl, MW 403.68 g/mol) used for the identification and quantification of trace impurities in APIs.
Clopidogrel Impurity 83 (C17H16Cl2N2O3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Clopidogrel Impurity 83 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16Cl2N2O3 HCl |
| Molecular Weight | 403.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Clopidogrel Standards
- Clopidogrel Impurity 74 (CAS 1008008-56-7)
- Clopidogrel Impurity 82 (CAS 1015247-87-6)
- rac-Clopidogrel EP Impurity A HCl (CAS 1015247-88-7)
- rac Clopidogrel [(tert-Butylcarbonyl)oxy]methyl ester (CAS 1043913-82-1)
- 2-Oxo Clopidogrel (Mixture of Diastereomers) (CAS 109904-27-0)
- Clopidogrel Impurity 42 (CAS 109904-36-1)
- cis-Clopidogrel glutathione disulfide, mixture of diastereomers (CAS 1118605-95-0)
- Clopidogrel Impurity 48 (CAS 111954-31-5)
Recommended Standards
- Glipizide Impurity 30 (CAS 3173-53-3)
- Fluticasone Furoate EP Impurity E (CAS 398454-97-2)
- Ceftopram lmpurity 44 (CAS CATO-C4X-135844)
- (E)-2-nitro-2-(phenylsulfonyl)acetaldehyde O-(2-bromobenzyl) oxime (CAS 339278-38-5)
- 4-(Methoxymethyl)-2,6-dimethylphenylboronic acid (CAS 1192107-39-3)
- (S)-Isobutyl 2-aminopropanoate (CAS 44921-72-4)
- 2-(2,5-dichlorophenyl)ethan-1-amine hydrochloride (CAS 1311317-57-3)
- 2,6-Diphenylpiperidin-4-one (CAS 5554-55-2)
- (5-((4-Chlorophenyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl acetate (CAS 318469-27-1)
- [Formaldehyde Schiff-base]-Semaglutide Impurity 136 X TFA Salt (CAS CATO-C4X-2226136)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com