8-Bromo-2-(4-(methylamino)piperidin-1-yl)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one CAS 2173992-17-9
| CAS No. | 2173992-17-9 |
| Molecular Formula | C25H25BrN6O2 |
| Molecular Weight | 521.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-Bromo-2-(4-(methylamino)piperidin-1-yl)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one (CAS 2173992-17-9) is a high-purity analytical reference standard with the molecular formula C25H25BrN6O2 and a molecular weight of 521.41 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 8-Bromo-2-(4-(methylamino)piperidin-1-yl)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 521.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H25BrN6O2 |
| Molecular Weight | 521.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 6 |
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Recommended Standards
- (S)-3-(4-((2,7-Naphthyridin-1-yl)amino)phenyl)-2-((2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino)propanoic acid (CAS 455264-31-0)
- Methyl 2-(2-(2,4-dichlorophenoxy)acetamido)-5-((2,4-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 505095-51-2)
- G-749 (CAS 1457983-28-6)
- Cephalosporin Impurity 3 (CAS 1269661-24-6)
- 6-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridine-2-carboxylic acid (CAS 1896831-02-9)
- 1-(2-bromo-1-fluoroethyl)-4-methoxybenzene (CAS 66472-42-2)
- Rac-(8S,8aS)-octahydro-8-indolizinamine dihydrochloride (CAS 1864003-55-3)
- 2,5-Dibenzyltetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione (CAS 165893-99-2)
- 3-Cyclopropoxy-4-(trifluoromethyl)picolinonitrile (CAS 1243405-27-7)
- Spiro[chromene-2,4'-piperidine] hydrochloride (CAS 1047655-63-9)
- Z-Glu-Tyr-OH (CAS 988-75-0)
- Revefenacin Impurity 51 (CAS CATO-C4X-203151)
- 1-(Pyridin-2-yl)hexane-1,6-diamine (CAS 904813-53-2)
- D-[Phe]6-Liraglutide (CAS CATO-C4X-199235)
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