5-Bromo-4-chloro-1H-indole CAS 217656-69-4
| CAS No. | 217656-69-4 |
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Bromo-4-chloro-1H-indole.
CATO supplies 5-Bromo-4-chloro-1H-indole (CAS 217656-69-4), a certified reference material (molecular formula C8H5BrClN, MW 230.49 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H5BrClN, 5-Bromo-4-chloro-1H-indole contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 230.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromo-4-chloro-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BrClN |
| Molecular Weight | 230.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-(3-Bromo-5-chlorophenyl)acetonitrile (CAS 1056454-88-6)
- 2-(5-Bromo-2-chlorophenyl)acetonitrile (CAS 1057216-52-0)
- 3-Bromo-6-chloro-1H-indole (CAS 1094641-40-3)
- 3-Bromo-4-chloro-1H-indole (CAS 1181332-74-0)
- 4-Bromo-5-chloro-1H-indole (CAS 1191028-48-4)
- 6-Bromo-5-chloro-1H-indole (CAS 1191028-50-8)
- 5-Bromo-6-chloroindole (CAS 122531-09-3)
- 4-Bromo-5-chloro-2-methylbenzonitrile (CAS 1228376-18-8)
Recommended Standards
- 5-(Bromomethyl)-2-chlorobenzonitrile (CAS 99613-64-6)
- 5-Bromo-4-chloro-2-methylbenzonitrile (CAS 2090528-94-0)
- 4-Bromo-6-chloro-1H-indole (CAS 885519-23-3)
- 6-Bromo-3-chloro-1H-indole (CAS 57916-08-2)
- (R)-1-((2S,4R,5R)-5-Hydroxy-2-phenyl-1,3-dioxan-4-yl)ethane-1,2-diol (CAS 80924-06-7)
- 5-chloro-1-methyl-1H-indole-3-carbaldehyde (CAS 412284-65-2)
- 2-(Furan-2-yl)-1H-benzo[d]imidazol-1-ol (CAS 691353-44-3)
- 3-Piperidinylmethyl tetrahydro-2H-pyran-4-carboxylate hydrochloride (CAS 1220020-91-6)
- Methyl 3-bromo-4,5-dimethylbenzoate (CAS 1515085-81-0)
- 2-Ethoxy-1-(pent-4-en-1-yl)pyrimidin-4(1H)-one (CAS 388567-10-0)
- 2-((1-(4-Chlorophenyl)ethyl)amino)-N-methylacetamide (CAS 1095519-82-6)
- Methyl 2-(2-fluoroethoxy)acetate (CAS 149605-54-9)
- (1R,2R)-2-(Methylamino)cyclohexanol (CAS 21651-83-2)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
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