3-hydroxy-5-(trifluoromethyl)thiophene-2-carboxylic acid CAS 217959-85-8
| CAS No. | 217959-85-8 |
| Molecular Formula | C6H3F3O3S |
| Molecular Weight | 212.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-hydroxy-5-(trifluoromethyl)thiophene-2-carboxylic acid (CAS 217959-85-8) is a high-purity analytical reference standard with the molecular formula C6H3F3O3S and a molecular weight of 212.15 g/mol.
Structurally, 3-hydroxy-5-(trifluoromethyl)thiophene-2-carboxylic acid (C6H3F3O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 212.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-hydroxy-5-(trifluoromethyl)thiophene-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3F3O3S |
| Molecular Weight | 212.15 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related hydroxy Standards
- Ethyl 4-hydroxy-5-nitropicolinate (CAS 1196157-33-1)
- 2-Hydroxy-4-methoxy-1,3-benzenedicarboxylic Acid (CAS 1202796-52-8)
- 7-Hydroxy-6-methyl-8-nitro-2,3-dihydro-5H-oxazolo[3,2-a]pyridin-5-one (CAS 1303510-26-0)
- methyl 2-hydroxy-6-methyl-3-nitropyridine-4-carboxylate (CAS 1803607-72-8)
- Ethyl 4-hydroxy-3-nitropicolinate (CAS 1806339-13-8)
- 4-Hydroxy-5-methoxyisophthalic acid (CAS 2134-91-0)
- Methyl 3-hydroxy-4-(4-hydroxy-5-oxofuran-2(5H)-ylidene)but-2-enoate (CAS 351069-94-8)
- N-(4-hydroxy-6-methyl-5-nitropyrimidin-2-yl)acetamide (CAS 299916-90-8)
Recommended Standards
- 3-(Difluoromethyl)-7-hydroxy-2H-chromen-2-one (CAS 2102410-22-8)
- 4-(2,4-Difluorophenyl)-4-oxobut-2-enoic acid (CAS 83844-25-1)
- 2-Amino-4-(trifluoromethyl)thiazole-5-carboxylic Acid (CAS 239135-55-8)
- 4-(3,4-Difluoro-phenyl)-4-oxo-but-2-enoic acid (CAS 83844-24-0)
- 2-Cyclopentyl-4-ethylpyrimidine-5-carboxylic acid (CAS 1248037-71-9)
- 5-Fluoro-1H-pyrrolo[2,3-c]pyridine-2-carbaldehyde (CAS 2169453-85-2)
- 3-(5,5-Dimethylpyrrolidin-2-ylidene)-3H-indole (CAS 802859-50-3)
- N-(4-acetylphenyl)-5-methylthiophene-2-carboxamide (CAS 942676-69-9)
- n-Hydroxy-2-methyl-2-phenylpropanamide (CAS 107955-92-0)
- 4-((3-(p-Tolyl)-1,2,4-oxadiazol-5-yl)methoxy)benzaldehyde (CAS 1119415-06-3)
- tert-Butyl ((1R,2S)-2-aminocyclobutyl)carbamate (CAS 1932344-68-7)
- 2-Allyl-6-phenyl-1,2,3,6-tetrahydropyridine (CAS 899015-33-9)
- 1-Methyl-7-phenyl-3,4-dihydroisoquinoline (CAS 24464-44-6)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com