Ethyl 2-fluoro-4-hydroxybenzoate CAS 217978-01-3
| CAS No. | 217978-01-3 |
| Molecular Formula | C9H9FO3 |
| Molecular Weight | 184.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Ethyl 2-fluoro-4-hydroxybenzoate (CAS 217978-01-3), a certified reference material (molecular formula C9H9FO3, MW 184.16 g/mol) for analytical method development and quality control.
Ethyl 2-fluoro-4-hydroxybenzoate (C9H9FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9FO3 |
| Molecular Weight | 184.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
Related Ethyl Standards
- 3-fluoro-4-(2-hydroxyethoxy)benzaldehyde (CAS 1004779-24-1)
- 2-(3-Fluoro-2-methoxyphenyl)acetic acid (CAS 1017778-30-1)
- Ethyl 2-fluoro-3-hydroxybenzoate (CAS 105836-28-0)
- Methyl 3-fluoro-2-methoxybenzoate (CAS 106428-04-0)
- 1-(2-Fluoro-4-hydroxy-5-methoxyphenyl)ethan-1-one (CAS 1065076-49-4)
- (7-Fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol (CAS 107618-09-7)
- 3-Fluoro-4-methoxy-2-methylbenzoic acid (CAS 1093989-12-8)
- (S)-(7-Fluoro-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol (CAS 1106941-42-7)
Recommended Standards
- Ethyl 2,3,3-trifluoro-2-methylbutanoate (CAS 2260710-24-3)
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- 3-Chloro-2-fluoro-5-methoxypyridine (CAS 1227574-55-1)
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- 1-(7-Bromo-2,3-dihydro-1H-inden-5-yl)ethan-1-ol (CAS 1784314-05-1)
- tert-Butyl 3-hydrazinylazetidine-1-carboxylate hydrochloride (CAS 1998216-27-5)
- 2,4-Dimethyl 3-{2-[4-(pyridin-2-yl)piperazin-1-yl]acetyl}-1,3-thiazolidine-2,4-dicarboxylate (CAS 318951-84-7)
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