Paclitaxel Impurity 49 CAS 2180123-01-5

Description

Compared with other compounds in its class, the molecular weight of 403.43 g/mol gives Paclitaxel Impurity 49 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Paclitaxel Impurity 49 (CAS 2180123-01-5) is a certified pharmaceutical impurity reference standard with the molecular formula C24H21NO5 and a molecular weight of 403.43 g/mol.

Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Paclitaxel Impurity 49 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 403.43 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Paclitaxel Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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