Olaparib Impurity 21 CAS 218301-22-5
| CAS No. | 218301-22-5 |
| Molecular Formula | C8H4FNO |
| Molecular Weight | 149.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C8H4FNO, Olaparib Impurity 21 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 149.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Olaparib Impurity 21 (CAS 218301-22-5, C8H4FNO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Olaparib Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4FNO |
| Molecular Weight | 149.12 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Olaparib Standards
- Olaparib Impurity 31 (CAS 16859-59-9)
- Olaparib Impurity 78 (CAS 73289-79-9)
- Olaparib Impurity 67 (CAS 227609-85-0)
- Olaparib Impurity 48 (CAS 59878-57-8)
- Olaparib Impurity 62 (CAS 76816-54-1)
- Olaparib Impurity 74 (CAS 39968-33-7)
- Olaparib Impurity 71 (CAS 2592-95-2)
- Olaparib impurity 144 (CAS CATO-C4X-1135144)
Recommended Standards
- 2-Cyano-4-fluorobenzaldehyde (CAS 77532-90-2)
- 2,3,6-Trifluorotoluene(Methyl D3) (CAS 1208075-33-5)
- 4-Fluorobenzoyl cyanide (CAS 658-13-9)
- 2,4,6-Trifluorotoluene(Methyl D3) (CAS 1208076-21-4)
- Duloxetine Impurity (CAS CATO-C4X-133626)
- Perospirone Impurity 33 (CAS CATO-C4X-245833)
- Ornidazole Impurity 81 (CAS CATO-C4X-133181)
- 2-(4-chlorophenoxy)-2-methylpropanenitrile (CAS 24889-11-0)
- 1-[4-(6-Chloro-pyridazin-3-ylmethyl)-piperidin-1-yl]-ethanone (CAS 1316222-53-3)
- N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine (CAS 869355-20-4)
- methyl 2-(2-bromo-3-pyridyl)-2,2-difluoro-acetate (CAS 2761389-76-6)
- 4-(3-Bromopropoxy)-5-methoxy-2-nitrobenzoic acid (CAS 343308-52-1)
- Ethyl 8-(2-((4-methylpiperazin-1-yl)methyl)phenyl)-8-oxooctanoate (CAS 898762-75-9)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com