6-(4-Chloro-3,5-dimethylphenoxy)pyridin-3-amine CAS 218457-66-0
| CAS No. | 218457-66-0 |
| Molecular Formula | C13H13ClN2O |
| Molecular Weight | 248.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-(4-Chloro-3,5-dimethylphenoxy)pyridin-3-amine (C13H13ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 6-(4-Chloro-3,5-dimethylphenoxy)pyridin-3-amine (CAS 218457-66-0), a certified reference material (molecular formula C13H13ClN2O, MW 248.71 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H13ClN2O |
| Molecular Weight | 248.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
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- 5-Methyl-2,1,3-benzothiadiazole-4-sulfonyl chloride (CAS 3662-82-6)
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- Phenylacetic Acid Mustard (CAS 10477-72-2)
- 2',5'-Dimethyl-[1,1':4',1''-terphenyl]-4,4''-dicarbaldehyde (CAS 857412-04-5)
- 3-Chloro-5-formylbenzenesulfonyl chloride (CAS 1393540-34-5)
- Methyl 4-chloro-2-hydroxy-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1820813-94-2)
- Methyl 6-morpholinopyrimidine-4-carboxylate (CAS 1949816-04-9)
- 3'-Hydroxy-6'-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one (CAS 129787-63-9)
- 1-Benzyl 5-methyl (2S)-2-{[(benzyloxy)carbonyl]amino}pentanedioate (CAS 105299-31-8)
- 3-Fluoro-4-(3-phenylpropoxy)aniline (CAS 112773-06-5)
- 1H-pyrrolo[2,3-c]pyridine-1-carboxylic acid (CAS 2216750-82-0)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
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