(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one (4S)-4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3-dimethyl-2-hexanone 218614-14-3 CAS 218614-14-3

Purity 97%+In StockPharmaceutical Standards
CAS No.218614-14-3
Molecular FormulaC20H44O3Si2
Molecular Weight388.73 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one (4S)-4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3-dimethyl-2-hexanone 218614-14-3 CAS 218614-14-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one (4S)-4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3-dimethyl-2-hexanone 218614-14-3.

(4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one (4S)-4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3-dimethyl-2-hexanone 218614-14-3 (CAS 218614-14-3) is a high-purity analytical reference standard with the molecular formula C20H44O3Si2 and a molecular weight of 388.73 g/mol.

The molecular framework of (4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one (4S)-4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3-dimethyl-2-hexanone 218614-14-3 (C20H44O3Si2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures (4S)-4,6-Bis-{[tert-butyldimethylsilyl)oxy]}-3,3-dimethylhexan-2-one (4S)-4,6-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3-dimethyl-2-hexanone 218614-14-3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC20H44O3Si2
Molecular Weight388.73 g/mol
Purity97%+
StorageStore at room temperature, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)-1.0
CAS Registry Year (est.)2019

Recommended Standards

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