2-(Quinolin-3-yl)acetamide CAS 21863-59-2
| CAS No. | 21863-59-2 |
| Molecular Formula | C18H20FNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Quinolin-3-yl)acetamide (CAS 21863-59-2), a certified reference material (molecular formula C18H20FNOHCl, MW 321.82 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-(Quinolin-3-yl)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 321.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20FNO HCl |
| Molecular Weight | 321.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Quinolin Standards
- 4-[2-(quinolin-2-yl)ethenyl]benzoic acid (CAS 1000277-67-7)
- (2-Methyl-quinolin-6-yl)-acetic acid (CAS 1000542-76-6)
- 2-(Quinolin-3-yl)ethan-1-ol (CAS 1000548-45-7)
- Methyl 2-(quinolin-8-yl)acetate (CAS 100063-13-6)
- Quinolin-6-yl 2,2,2-trifluoroacetate (CAS 1000775-18-7)
- (R)-1-(Quinolin-4-yl)ethan-1-amine (CAS 1001906-55-3)
- 6-(Quinolin-2-yl)pyridin-2(1H)-one (CAS 1006365-14-5)
- 1-(Quinolin-6-yl)cyclopropanecarbonitrile (CAS 1006875-93-9)
Recommended Standards
- (3AS,8aR)-2-(pyrazin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole (CAS 2757082-80-5)
- Methyl 2-oxo-4,4-diphenylcyclopentanecarboxylate (CAS 819802-98-7)
- 1-(2-Amino-3,4-dimethoxyphenyl)ethan-1-one (CAS 49701-79-3)
- tert-Butyl 19-(tosyloxy)-3,6,9,12,15-pentaoxanonadecanoate (CAS 2681388-12-3)
- 3-(3-(Methoxycarbonyl)phenyl)propiolic acid (CAS 1391631-70-1)
- 4-Iodo-2-isopropyl-1-methyl-1H-imidazole (CAS 851870-24-1)
- 2-(6-Bromo-2-cyano-3-methoxyphenyl)acetic acid (CAS 1805528-81-7)
- 2,3-Dimethoxy-6-fluorobenzyl amine (CAS 1260855-36-4)
- 3-Bromo-5-(2-fluoroethoxy)pyridine (CAS 1241752-26-0)
- Des-Gly29,30-Tirzepatide (CAS CATO-CPTD788944)
Why CATO?
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