4-Hydroxy-3-methylbenzofuran-2(3H)-one CAS 21872-07-1
| CAS No. | 21872-07-1 |
| Molecular Formula | C9H8O3 |
| Molecular Weight | 164.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Hydroxy-3-methylbenzofuran-2(3H)-one (CAS 21872-07-1), a certified reference material (molecular formula C9H8O3, MW 164.16 g/mol) for analytical method development and quality control.
The molecular framework of 4-Hydroxy-3-methylbenzofuran-2(3H)-one (C9H8O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Hydroxy-3-methylbenzofuran-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8O3 |
| Molecular Weight | 164.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
Related Hydroxy Standards
- 3-Hydroxy-2-(3-hydroxyphenyl)prop-2-enal (CAS 105899-68-1)
- 4-Hydroxy-2-(hydroxymethyl)benzimidazole (CAS 116345-47-2)
- 5-Hydroxy-4-methyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 1190316-54-1)
- 5-Hydroxy-4-methylisobenzofuran-1(3H)-one (CAS 1194700-73-6)
- 2-Hydroxy-7,8-dihydro-1,6-naphthyridin-5(6H)-one (CAS 1251033-14-3)
- 3-Hydroxy-6-methyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one (CAS 1391732-76-5)
- 1-Hydroxy-2-methyl-1H-1,3-benzodiazol-3-ium-3-olate (CAS 15966-52-6)
- 3-Hydroxy-6-methylisobenzofuran-1(3H)-one (CAS 177166-16-4)
Recommended Standards
- 4-Hydrazinyl-3-methylisoxazolo[5,4-b]pyridine (CAS 651054-75-0)
- 4-Hydroxy-5-methylisophthalaldehyde (CAS 3328-73-2)
- 4-Formyl-3-methylbenzoic Acid (CAS 24078-23-7)
- 4-Hydroxy-6-methyl-1-benzofuran-3(2H)-one (CAS 929339-01-5)
- 1-(Azetidin-1-yl)-2-(3-bromophenoxy)ethan-1-one (CAS 1088225-09-5)
- 1-Phenyl-1H-indole-3-carboxylic acid (CAS 244090-34-4)
- Ethyl 6-fluoroisoquinoline-3-carboxylate (CAS 1822846-09-2)
- Methyl 2-(2-fluoro-5-methylphenyl)propanoate (CAS 1249660-38-5)
- 4-(5-Phenyl-1,2,4-oxadiazol-3-yl)piperidine hydrochloride (CAS 280110-74-9)
- 2-Chloro-5-((4,5-dichloro-2-methyl-1H-imidazol-1-yl)methyl)pyridine (CAS 1245570-11-9)
- 4-Bromo-3-chloro-2-fluorobenzene-1-sulfonyl chloride (CAS 1208077-08-0)
- 2-(6-Cyano-5-(difluoromethyl)-3-hydroxypyridin-2-yl)acetic acid (CAS 1806949-88-1)
- 2-methyl-1-(5-nitro-1,2,3,4-tetrahydroisoquinolin-2-yl)propan-2-ol (CAS 1461707-42-5)
- Endo-Pro36-Tirzepatide (CAS CATO-CPTD788688)
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