6-chloro-2-methylpyridin-3-ol CAS 218770-02-6
| CAS No. | 218770-02-6 |
| Molecular Formula | C6H12ClNO |
| Molecular Weight | 149.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-chloro-2-methylpyridin-3-ol is closely related to an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-chloro-2-methylpyridin-3-ol (CAS 218770-02-6) is a high-purity analytical reference standard with the molecular formula C6H12ClNO and a molecular weight of 149.62 g/mol.
The molecular framework of 6-chloro-2-methylpyridin-3-ol (C6H12ClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-chloro-2-methylpyridin-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H12ClNO |
| Molecular Weight | 149.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 5-chloro-3-methylpyrazin-2-amine (CAS 1001050-30-1)
- 6-chloro-3-methyl-pyridazin-4-amine (CAS 1195683-49-8)
- 2-Chloro-6-methoxypyridine (CAS 17228-64-7)
- 6-chloro-2-methylpyrimidin-4-amine (CAS 1749-68-4)
- (4-chloro-3-pyridyl)methanol (CAS 189449-41-0)
- 1-Chloro-3-(2-Propen-1-ylamino)-2-Propanol (CAS 950820-31-2)
- 2-Chloro-N,N-dimethylbutanamide (CAS 59843-83-3)
- 2-Chloro-n-isobutylacetamide (CAS 32461-83-9)
Recommended Standards
- 6-Aminohexanoyl chloride (CAS 66678-88-4)
- 6-chloro-5-methyl-pyridazin-4-amine (CAS 2387601-30-9)
- 5-chloro-6-methylpyrazin-2-amine (CAS 453548-87-3)
- carbamoyl chloride (CAS 341969-98-0)
- 2,4-Dimethylbenzylmagnesium chloride (CAS 107549-24-6)
- 2-Methoxy-N-(3-methylpentan-2-yl)pyridin-3-amine (CAS 1157520-80-3)
- 1-(4-(1,5-Dimethyl-1h-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-amine (CAS 1170294-71-9)
- Methyl 1-(2-hydroxyethyl)-1H-indazole-3-carboxylate (CAS 1352537-95-1)
- 2-[N-[2-(Fmoc-amino)ethyl]-2-[2-[[(benzhydryloxy)carbonyl]amino]-6-oxo-1H-purin-9(6H)-yl]acetamido]acetic Acid (CAS 186046-83-3)
- 5-Chloroisoquinolin-6-ol (CAS 918488-41-2)
- Keto Benzylated Ezetimibe (CAS 190595-65-4)
- Methyl 4-[(4-methoxy-4-oxobutyl)amino]benzoate (CAS 1820673-98-0)
- 2-(Piperidin-4-yloxy)thiazole hydrochloride (CAS 1185314-68-4)
- Semaglutide impurity 210 (CAS CATO-C4X-2226210)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com