2-(4-Oxopiperidin-1-yl)acetic acid CAS 218772-96-4
| CAS No. | 218772-96-4 |
| Molecular Formula | C7H11NO3 |
| Molecular Weight | 157.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(4-Oxopiperidin-1-yl)acetic acid (C7H11NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-(4-Oxopiperidin-1-yl)acetic acid (CAS 218772-96-4) is a high-purity analytical reference standard with the molecular formula C7H11NO3 and a molecular weight of 157.17 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Oxopiperidin-1-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H11NO3 |
| Molecular Weight | 157.17 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2019 |
| Nitrogen Atoms | 1 |
Related Oxopiperidin Standards
- 2-(2-Oxopiperidin-1-yl)acetic acid (CAS 72253-28-2)
- 2-(2-Oxopiperidin-4-yl)acetic acid (CAS 32741-96-1)
- 2-(3-Oxopiperidin-1-yl)acetic acid (CAS 728857-06-5)
- 2-(6-Oxopiperidin-2-yl)acetic acid (CAS 66654-69-1)
- 2-(6-Oxopiperidin-3-yl)acetic acid (CAS 933753-48-1)
- 2-(6-oxopiperidin-2-yl)acetamide (CAS 1071661-20-5)
- (R)-3-(4-Oxopiperidin-1-yl)butanenitrile (CAS 856931-48-1)
- 3-(6-Oxopiperidin-3-yl)propanoic acid (CAS 1150618-37-3)
Recommended Standards
- 2-(4,5-Dihydro-1H-imidazol-2-yl)-N-methylhydrazinecarboxamide (CAS 782390-01-6)
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- 2-(5-Oxopyrrolidin-2-yl)acetohydrazide (CAS 89691-71-4)
- 2-(3-Methylpyridin-2-yl)malononitrile (CAS 62019-63-0)
- 1-((4-Butylphenyl)amino)-4-hydroxyanthracene-9,10-dione (CAS 71334-38-8)
- 5-Amino-8-methylquinoline (CAS 50358-40-2)
- 3-(3-Chloropyridin-4-yl)-1,1,1-trifluoropropan-2-one (CAS 1485704-19-5)
- Spermine Impurity 2 (CAS CATO-C4X-33932)
- 2-Nitro-3-vinylpyridine (CAS 844503-09-9)
- Ethyl 2-(1-methylcyclopropyl)acetate (CAS 1071112-99-6)
- 1,1,1-Trifluoro-3-(1,2,3,4-tetrahydronaphthalen-1-yl)propan-2-one (CAS 1272879-87-4)
- 2-(5-Cyclobutyl-1,2,4-oxadiazol-3-yl)morpholine hydrochloride (CAS 1779123-52-2)
- 4-Methyl-3-(1-oxoisoindolin-2-yl)pentanoic acid (CAS 866144-51-6)
- SAMS Peptide (CAS 125911-68-4)
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